Results 141 to 150 of about 106,926 (311)

Domination and forcing

open access: yes, 2018
This thesis comprises the results of five research papers on domination and zero forcing. In "Largest Domination Number and Smallest Independence Number of Forests with given Degree Sequence" (Gentner, Henning, Rautenbach, 2016) and "Smallest Domination
Gentner, Michael
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Terre, seigneuries, monarchie en Castille, un parcours historiographique

open access: yesL'Atelier du CRH
This article offers a historiographical survey of studies on lordship and land control in the Castilian sphere over the course of a long second twentieth century.
Antoine Roullet
doaj   +1 more source

On the equality of domination number and 2-domination number

open access: yesDiscussiones Mathematicae Graph Theory
The 2-domination number $γ_2(G)$ of a graph $G$ is the minimum cardinality of a set $ D \subseteq V(G) $ for which every vertex outside $ D $ is adjacent to at least two vertices in $ D $. Clearly, $ γ_2(G) $ cannot be smaller than the domination number $ γ(G) $.
Gülnaz Boruzanli Ekinci, Csilla Bujtás
openaire   +5 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Some remarks on the pointwise sparse domination

open access: yes, 2019
We obtain an improved version of the pointwise sparse domination principle established by Lerner (N Y J Math 22:341–349, 2016). This allows us to determine nearly minimal assumptions on a singular integral operator T for which it admits a sparse ...
Lerner, Andrei K.   +1 more
core   +1 more source

Some necessary conditions for graphs with extremal connected 2-domination number [PDF]

open access: yesDiscrete Mathematics Letters
Piyawat Wongthongcue   +1 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

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