Results 51 to 60 of about 46,459 (294)
String-dominated cosmology [PDF]
If string theory controls physics at the string scale, the dynamics of the early universe before the GUT era will be governed by the low-energy string equations of motion. Studying these equations for FRW spacetimes, we find that depending on the initial conditions when the stringy era starts, and on the time when it ends, there are a wide variety of ...
Goldwirth, Dalia S., Perry, Malcolm J.
openaire +3 more sources
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Bounds on Global Total Domination in Graphs [PDF]
A subset $S$ of vertices in a graph $G$ is a \textit{global total dominating set}, or just GTDS, if $S$ is a \textit{total dominating set} of both $G$ and $\overline{G}$.
Nader Jafari Rad, Elahe Sharifi
doaj
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Instrumentalització de les passions, regulació social i transcendència del poder en el Hanfeizi
Aquest article té el propòsit fonamental de presentar, encara que sigui de manera esquemàtica, alguns dels elements fonamentals sobre els quals se sosté la proposta política i filosòfica del Hanfeizi, un dels texts més importants de la Xina preimperial ...
Albert Galvany
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The Concept of Violence in the Evolution of Nietzsche’s Thought
The aim of this paper is to present the idea of violence in Nietzsche’s work, seen as a basic principle that organizes and unites different elements of his philosophy.
Paweł Pieniążek
doaj +1 more source
Stochastic dominance, regret dominance and regret-theoretic dominance
It is well known that stochastic dominance alone is insufficient for ensuring preferences when individuals experience regret. In this paper, we study two additional notions of dominance: (a) regret-theoretic dominance, which characterizes preferences in regret theory and (b) regret dominance, which characterizes preferences in mean-risk models with ...
Chin Hon Tan, Joseph C. Hartman
openaire +1 more source

