Results 51 to 60 of about 715,404 (258)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Hn-Domination in Graphs

open access: yesBaghdad Science Journal, 2019
The aim of this article is to introduce a new definition of domination number in graphs called hn-domination number denoted by . This paper presents some properties which show the concepts of connected and independent hn-domination.
Omran Et al.
semanticscholar   +1 more source

The bondage number of random graphs [PDF]

open access: yes, 2016
A dominating set of a graph is a subset $D$ of its vertices such that every vertex not in $D$ is adjacent to at least one member of $D$. The domination number of a graph $G$ is the number of vertices in a smallest dominating set of $G$.
Mitsche, Dieter   +2 more
core   +2 more sources

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Elusive Domination and the Fate of Critique in Neo-participative Management: A French Pragmatist Approach

open access: yesOrganization Studies, 2019
In this theoretical paper we investigate how domination has adapted to the new social settings of a flexible and pluralist economy. Building on French pragmatic sociology, we propose an understanding of organizational domination whereby workers are ...
Thibault Daudigeos   +4 more
semanticscholar   +1 more source

Stochastic dominance, regret dominance and regret-theoretic dominance

open access: yesEURO Journal on Decision Processes, 2013
It is well known that stochastic dominance alone is insufficient for ensuring preferences when individuals experience regret. In this paper, we study two additional notions of dominance: (a) regret-theoretic dominance, which characterizes preferences in regret theory and (b) regret dominance, which characterizes preferences in mean-risk models with ...
Chin Hon Tan, Joseph C. Hartman
openaire   +1 more source

Domination Across Borders: An Introduction [PDF]

open access: yes, 2015
This chapter explores the different dimensions of domination, including whether it has a structural approach, its relation to race and imperialism, and how non-domination can be institutionalized and achieved at a global ...
Buckinx, Barbara   +2 more
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Weber’s theory of domination and post-communist capitalisms

open access: yes, 2016
This article has four main objectives. First, it introduces the ideal types of domination of Weber. Contrary to the received wisdom, which knows only “three ideal types” (traditional, charismatic and legal rational) I present the “fourth” type of ...
I. Szelenyi
semanticscholar   +1 more source

Domination and Fractional Domination in Digraphs

open access: yesThe Electronic Journal of Combinatorics, 2018
In this paper, we investigate the relation between the (fractional) domination number of a digraph $G$ and the independence number of its underlying graph, denoted by $\alpha(G)$. More precisely, we prove that every digraph $G$ on $n$ vertices has fractional domination number at most $2\alpha(G)$ and domination number at most $2\alpha(G) \cdot \log{n}$.
Harutyunyan, Ararat   +3 more
openaire   +5 more sources

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