Results 71 to 80 of about 44,708 (295)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Explorer les politiques de la langue et de l’infrastructure

open access: yesRevue d'anthropologie des connaissances
Analysing how journals operate is fundamental to understand how the academic world works, at a time when the impact factor has become a major sign of research quality.
Leandro Rodriguez Medina   +1 more
doaj   +1 more source

La prostitution sur Internet : Entre marchandisation de la sexualité et contractualisation de relations affectives

open access: yesGenre, Sexualité et Société, 2009
The development of the new information and communication technologies has profoundly modified the landscape of prostitution in recent years, in particular by favoring the growth of escort services, a form of prostitution which combines sexual and ...
Sylvie Bigot
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Some Reflections on the Moral Reality of Social Power

open access: yesReligions
Power is often understood as the sheer use of force in social relations. While power is frequently expressed and experienced in these terms, it is also necessary for the generation, sustenance, and enhancement of life in all its forms.
Charles S. Brown
doaj   +1 more source

La domination sociale dans le contexte contemporain

open access: yesRecherches Sociologiques et Anthropologiques, 2014
The concept of domination has been at work in sociology for over a century but the current socio-economic conditions are no longer those that surrounded its emergence.
Caroline Guibet Lafaye
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Régimes d’action et rapports de pouvoir. Vers un approfondissement de la théorie bourdieusienne de la domination ?

open access: yesRecherches Sociologiques et Anthropologiques, 2015
In Bourdieu’s thought, the social and symbolic relationships between groups are conceived of as relationships of domination of an agonistic type. Such a representation of power fails to account for the diversity of power and domination relations and the ...
Georges Liénard, Éric Mangez
doaj   +1 more source

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