Results 81 to 90 of about 135,416 (202)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Some Reflections on the Moral Reality of Social Power
ReligionsPower is often understood as the sheer use of force in social relations. While power is frequently expressed and experienced in these terms, it is also necessary for the generation, sustenance, and enhancement of life in all its forms.
Charles S. Brown
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Affirmative domination in graphs. [PDF]
, 2016 A function f : V → {−1, 0, 1} is an affirmative dominating function of graph G satisfying the conditions that for every vertex u such that f(u) = 0 is adjacent to at least one vertex v for which f(v) = 1 and P u∈N(v) f(u) ≤ 1 for every v ∈ V .
Chaitra, V., Chaluvaraju, B.
core
, 2018 This thesis comprises the results of five research papers on domination and zero forcing. In "Largest Domination Number and Smallest Independence Number of Forests with given Degree Sequence" (Gentner, Henning, Rautenbach, 2016) and "Smallest Domination
Gentner, Michael
core +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Dimensions of Emancipation: Rethinking Subjectivity, Domination and Temporality in Feminist Theory
Redescriptions, 2016 “Emancipation” is one of the most opaque words in political language and political theory. It refers to the hope of overcoming all forms of domination, yet is articulated with the highly ambivalent notions of reason, progress, equality and liberty, and ...
Susanne Lettow
doaj +1 more source
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source