Results 91 to 100 of about 436,818 (327)
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
La dimension spatiale du travail des livreurs des plateformes
Carnets de Géographes, 2023 From a research based on interviews and non-participant observation, this article proposes an analysis of the spatial dimension of plateforms delivery men’s work (UberEats, Deliveroo), based on the case of Nantes metropolis.
Claire Burban
doaj
From Domination to Autonomy: Two Eras of Progress in World-sociological Perspective
Historicka Sociologie, 2015 In recent decades, the belief in progress that was widespread across the two centuries following the French Revolution has withered away. This article suggests, though, that the diagnosis of the end of progress can be used as an occasion to rethink what ...
Peter Wagner
doaj +1 more source
COLONIALISM TOWARDS CHINESE SOCIETY IN W. SOMERSET MAUGHAM’S THE PAINTED VEIL [PDF]
, 2013 In this thesis, the writer is interested to analyze colonialism in William Somerset Maugham’s The Painted Veil. The purposes of the thesis are to analyze how the British colonization works during the cholera epidemic in China, to analyze how the response
Pramesti , Endah
core
How long before the end of inflation were observable perturbations produced? [PDF]
, 2003 We reconsider the issue of the number of e-foldings before the end of inflation at which observable perturbations were generated. We determine a plausible upper limit on that number for the standard cosmology which is around 60, with the expectation that
A. A. Starobinsky +30 more
core +3 more sources
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Average value of solutions of the bipartite quadratic assignment problem and linkages to domination analysis [PDF]
, 2015 Ante Ćustić, Abraham P. Punnen
openalex +2 more sources
Humpty Dumpty domination on correlational data analysis in social welfare researches [PDF]
فصلنامه رفاه اجتماعی, 2023 Introduction Identifying and correct errors is essential to science, so propose the maxim that science is self correcting. While the err is humain is accepted reflected in philosophy of science especially in giving rise to the maxim that scientific ...
hamidreza oreyzi
doaj
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source