Results 101 to 110 of about 35,518 (310)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Forum on Recognition in Foreign Policy (Analysis) and (The Study of) Diplomacy [PDF]
Contexto InternacionalWhat if the quest for recognition, not power, rank or security, were the overriding objective of foreign policies? What if practices of recognition both empower and subjugate by fixing identities and reproducing the terms upon which agents become ...
Stefano Guzzini +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
A General Theory of Domination and Justice
, 2010 In all societies, past and present, many persons and groups have been subject to domination. Properly understood, domination is a great evil, the suffering of which ought to be minimized as far as possible.
Frank Lovett
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Human Possibilities: The Interaction of Biology and Culture
Interdisciplinary Journal of Partnership Studies, 2015 This article briefly describes the two main strands of a new unified theory about human nature and human possibilities: cultural transformation theory and bio-culturalism.
Riane Eisler
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Bilinear sparse domination for oscillatory integral operators
In this paper, we prove bilinear sparse domination bounds for a wide class of Fourierintegral operators of general rank, as well as oscillatory integral operators associated toHörmander symbol classes Smρ ,δ for all 0 ≤ ρ ≤ 1 and 0 ≤ δ < 1, a notable ...
Mattsson, Tobias, Mattsson, Tobias,
core +1 more source
Mary Shelley Biopic (2017): A filmic discourse analysis
CINEJ Cinema JournalThis work analyzes the discourses that compound Mary Shelley biopic (2017), concerning male domination and female resistance. To do so, the specific objectives are: to verify how this domination permeates the main character with a view to publish her ...
Thanya Araujo, Lívia Fernanda Silva
doaj +1 more source