Results 141 to 150 of about 35,518 (310)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Dialectics and Domination: Reflections on Social Action

open access: yes, 1983
The question is posed: can social activists be assisted by a conceptual scheme that is intelligent about the internal complexities of the social action process? A theoretical analysis considers the dialectic mode and the domination mode of social action.
Demaria W.
core   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Convex body domination for a class of multi-scale operators

open access: yes, 2023
The technique of sparse domination, i.e., dominating operators with sums of averages taken over sparsely distributed cubes, has seen rapid development recently within the realms of harmonic analysis.
Laukkarinen, Aapo
core  

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

Combinatorial analysis of line graphs: Domination, chromaticity, and Hamiltoniancity

open access: yes
Line graphs are afundamental class of graphs extensively studied for their structural properties and applications in diverse fields such as network design, optimization, and algorithm development.
Sakander Hayat   +4 more
core   +1 more source

Foucault: Husband or Laver? Some Tensions between Foucault and Feminism

open access: yesRevista Estudos Feministas, 2000
This paper explores some aspects of Foucault’s work that have been influential for feminist theory and politics. After a brief review of some of Foucault's contributions to the analysis of gender subordination, it identifies an area of convergence ...
Josefina Fernández
doaj  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

KARAKTERISTIK TULISAN NARASI FIKSI BERBAHASA ARAB MAHASISWA PENUTUR ASLI BAHASA INDONESIA

open access: yesBahasa dan Seni: Jurnal Bahasa, Sastra, Seni, dan Pengajarannya, 2011
This study is carried out to answer the research questions what are the characteristics of intrinsic elements, include is plot, character, and background   of the Arabic fictitious narrative writing of Indonesian language native students?
Nurhidayati Nurhidayati
doaj  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

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