Results 101 to 110 of about 10,563,621 (305)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Independent [1,2]-number versus independent domination number

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2017
A [1; 2]-set S in a graph G is a vertex subset such that every vertex not in S has at least one and at most two neighbors in it. If the additional requirement that the set be independent is added, the existence of such sets is not guaranteed in every ...
Aleid Sahar A.   +2 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

On the power domination number of the Cartesian product of graphs

open access: yesAKCE Int. J. Graphs Comb., 2019
We give a brief survey about the existing results on the power domination of the Cartesian product of graphs, and improve two of the results by determining the exact power domination numbers of two...
K. Koh, K. W. Soh
semanticscholar   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Rainbow game domination subdivision number of a graph [PDF]

open access: yesRomanian Journal of Mathematics and Computer Science, 2014
The rainbow game domination subdivision number of a graph G is defined by the following game. Two players D and A, D playing first, alternately mark or subdivide an edge of G which is not yet marked nor subdivided.
J. Amjadi
doaj  

Domination Number and Secure Resolving Sets in Cyclic Networks

open access: yesApplied and Computational Mathematics, 2023
Basma Mohamed, Mohamed Amin
semanticscholar   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Domination number of annulus triangulations

open access: yesTheory and Applications of Graphs, 2020
An {\em annulus triangulation} $G$ is a 2-connected plane graph with two disjoint faces $f_1$ and $f_2$ such that every face other than $f_1$ and $f_2$ are triangular, and that every vertex of $G$ is contained in the boundary cycle of $f_1$ or $f_2$.
Toshiki Abe   +2 more
doaj   +1 more source

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