Results 81 to 90 of about 9,423,140 (336)

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

On a Vizing-type Integer Domination Conjecture

open access: yesTheory and Applications of Graphs, 2020
Given a simple graph G, a dominating set in G is a set of vertices S such that every vertex not in S has a neighbor in S. Denote the domination number, which is the size of any minimum dominating set of G, by γ(G). For any integer k ≥ 1, a function f : V
Elliot Krop, Randy Davila
doaj   +1 more source

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

open access: yesFEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Vertex-edge perfect Roman domination number

open access: yesAIMS Mathematics, 2023
A vertex-edge perfect Roman dominating function on a graph $ G = (V, E) $ (denoted by ve-PRDF) is a function $ f:V\left(G\right)\longrightarrow\{0, 1, 2\} $ such that for every edge $ uv\in E $, $ \max\{f(u), f(v)\}\neq0 $, or $ u $ is adjacent to ...
Bana Al Subaiei   +2 more
doaj   +1 more source

On the domination number and the total domination number of Fibonacci cubes

open access: yesArs Mathematica Contemporanea, 2019
Fibonacci cubes are special subgraphs of the hypercube graphs. Their domination numbers and total domination numbers are obtained for some small dimensions by integer linear programming. For larger dimensions upper and lower bounds on these numbers are given.
openaire   +3 more sources

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Block Graphs with Large Paired Domination Multisubdivision Number

open access: yesDiscussiones Mathematicae Graph Theory, 2021
The paired domination multisubdivision number of a nonempty graph G, denoted by msdpr(G), is the smallest positive integer k such that there exists an edge which must be subdivided k times to increase the paired domination number of G.
Mynhardt Christina M., Raczek Joanna
doaj   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

On a Relation between the Perfect Roman Domination and Perfect Domination Numbers of a Tree

open access: yesMathematics, 2020
A dominating set in a graph G is a set of vertices S ⊆ V ( G ) such that any vertex of V − S is adjacent to at least one vertex of S .
Zehui Shao   +4 more
doaj   +1 more source

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