Results 81 to 90 of about 9,635,811 (355)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Equalityof Secure Domination and Inverse Secure Domination Numbers
Summary: Let \(G=(V,E)\) be a graph. Let \(D\) be a minimum secure dominating set of \(G\). If \(V-D\) contains a secure total dominating set \(D'\) of \(G\) then \(D'\) is called an inverse secure dominating set with respect to \(D\). The smallest cardinality of inverse secure dominating set of \(G\) is the secure domination number \(\gamma_s^{-1}(G)\)
openaire +2 more sources
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
On a Vizing-type Integer Domination Conjecture
Given a simple graph G, a dominating set in G is a set of vertices S such that every vertex not in S has a neighbor in S. Denote the domination number, which is the size of any minimum dominating set of G, by γ(G). For any integer k ≥ 1, a function f : V
Elliot Krop, Randy Davila
doaj +1 more source
On the domination number and the total domination number of Fibonacci cubes
Summary: Fibonacci cubes are special subgraphs of the hypercube graphs. Their domination numbers and total domination numbers are obtained for some small dimensions by integer linear programming. For larger dimensions upper and lower bounds on these numbers are given.
openaire +5 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Computation of Various Domination Numbers of Rolf Nevanlinna (RNP) Collaboration Graph
In this paper, we compute various Domination numbers like Outer Connected Domination (OCD), Doubly Connected Domination (DCD), Fair Domination (FD), Independence Domination (ID), 2-Packing (2-P) for Rolf Nevanlinna Prize Winners's Collaboration Graph ...
Yegnanarayanan V, Logeshwary B
doaj +1 more source
On the Secure Total Domination Number of Graphs
A total dominating set D of a graph G is said to be a secure total dominating set if for every vertex u ∈ V ( G ) \ D , there exists a vertex v ∈ D , which is adjacent to u, such that ( D \ { v } ) ∪ { u } is a total dominating set as well.
Abel Cabrera Martínez +2 more
semanticscholar +1 more source

