Results 231 to 240 of about 12,409,454 (287)

Stress Hyperglycemia Drives CD4+ T Cell PANoptosis and Postoperative Organ Injury via Monocyte‐Derived Succinate

Advanced Science, EarlyView.
High glucose is linked to reduced succinate dehydrogenase activity in CD14+ monocytes, accompanied by succinate accumulation and extracellular release. Extracellular succinate exacerbates mitochondrial ROS production and mtDNA release in CD4+ T cells. Cytosolic mtDNA then activates Z‐DNA binding protein 1 (ZBP1) and engages ZBP1‐associated inflammatory
Shuai Zhao, Xuemei Miao, Wei Luo, Tao Liu, Yang Wang, Jiaying Li, Di Fu, Weiyun Shen, Yan Luo, Kang Chen, Ruping Dai, Hui Li   +11 more
wiley   +1 more source

Regional Variation in Transplant Utilization and Agonal Times among Donation after Circulatory Death Lung Donors in the United States. [PDF]

Clin Transplant
Noda K, Coster JN, Zhang K, Lafayette A, Furukawa M, Sanchez PG.   +5 more
europepmc   +1 more source

Nanoparticle‐Mediated TIPE1 mRNA Delivery Enhances Paclitaxel Sensitivity in Triple‐Negative Breast Cancer by Modulating RAB7A Ubiquitination‐Associated Stability and Autophagy

Advanced Science, EarlyView.
TIPE1m NPs nanoparticles restore TIPE1 expression, promote RAB7A ubiquitination and degradation, suppress autophagic flux, and resensitize paclitaxel‐resistant triple‐negative breast cancer to therapy. ABSTRACT Acquired paclitaxel (PTX) resistance remains a major obstacle in triple‐negative breast cancer (TNBC) treatment.
Wei Hu, Qishuai Chen, Yan Ma, Yang Liu, Xianing Dong, Wenjuan Wei, Jianxin Du, Shusheng Qiu, Maojin Tian, Peiqing Zhao   +9 more
wiley   +1 more source

Five-year experience of heart transplantation following donation after circulatory death. [PDF]

J Thorac Cardiovasc Surg
Benkert AR, Jawitz OK, Lobo AA, Casalinova S, Goel D, Dewan KC, Patel CB, DeVore AD, Schroder JN, Milano CA, Keenan JE.   +10 more
europepmc   +1 more source

Donation after circulatory death; cholangiopathy in the machine age. [PDF]

Curr Opin Organ Transplant
Currie IS, Hunt FM.
europepmc   +1 more source

Donation After Circulatory Death Heart Transplant Without Preimplant Reanimation Using Rapid Ultraoxygenated Recovery.

JAMA
Williams AM, Trahanas J, Bommareddi S, McGann KC, Ahmad A, Lima B, Wang CC, Petrovic M, Devries S, Lowman J, Absi T, Quintana E, Siddiqi H, Amancherla K, Brinkley M, Tsai S, Menachem JN, Pedrotty D, Rali AS, Sacks S, Zalawadiya S, Lepore J, Pretorius M, Schlendorf K, Bacchetta M, Shah AS.   +25 more
europepmc   +1 more source

Ex vivo lung perfusion in donation after circulatory death lung transplantation: A systematic review and meta-analysis. [PDF]

JHLT Open
Costa BS, Coelho BC, Grillo ITC, da Nobrega Oliveira REN, Caldonazo T, Passos FS, Carvalho EA.   +6 more
europepmc   +1 more source

XBP1s-Orchestrated Soluble Mediators: Participants of Oxidative Stress in Renal Ischemia-Reperfusion Injury Following Donation After Circulatory Death. [PDF]

Mediators Inflamm
Zhang J, Zhao Y, Zhong J, Ding H, Chen W, Li D, Chen X, Zhu D, Liao G, Gong N.   +9 more
europepmc   +1 more source

Listing for Pediatric Donation After Circulatory Death Heart Transplantation Is Associated With Improved Waitlist Outcomes. [PDF]

J Am Heart Assoc
Catalano MA, Shin M, Toubat O, Rastogi R, Beqaj H, Iyengar A, Smood BF, Toomey N, Edelson JB, Rossano JW, O'Connor MJ, Ahmed H, Gaynor JW, Maeda K, Mavroudis CD.   +14 more
europepmc   +1 more source

Sex differences in cardiac graft recovery and pathophysiologic changes in a rat model of donation after circulatory death. [PDF]

Sci Rep
Clavier A, Graf S, Helmer A, Lagger D, Egle M, Segiser A, Siepe M, Arnold M, Longnus S.   +8 more
europepmc   +1 more source