Results 1 to 10 of about 262,300 (219)

Identification of ubiquitination-related signature genes for predicting kidney transplant rejection

Scientific Reports
Kidney transplant rejection (KTR) poses significant challenges to long-term graft survival, with involvement from ubiquitination-related genes (URGs) in immune modulation. This study aimed to identify key URGs linked to KTR and develop a predictive model
Zhengfei Shan, Shengqiang Yu, Jiantao Wang, Jianxin Cui, Haijian Wei, Xiaohua Fu, Chen Zhang, Chengjun Zhang   +7 more
doaj   +1 more source

Impact of music on pain perception during office-based transperineal prostate biopsy: a prospective non-randomized study

Scientific Reports
Although music has been shown to alleviate pain and anxiety during transrectal PBx, limited evidence is available regarding its impact in the transperineal (TP) setting. This study aimed to investigate the effect of music on pain perception during office-
Luca Montrone, Marco Finati, Anna Ricapito, Antonio Fanelli, Nicolò Giannoccaro, Francesco Troiano, Giuliano Ciavotta, Ugo Giovanni Falagario, Luigi Cormio, Gian Maria Busetto, Carlo Bettocchi, Oscar Selvaggio, Giuseppe Carrieri   +12 more
doaj   +1 more source

Sirtuin 3 in renal diseases and aging: From mechanisms to potential therapies

Pharmacological Research
The longevity protein sirtuins (SIRTs) belong to a family of nicotinamide adenine dinucleotide (NAD+)-dependent deacetylases. In mammals, SIRTs comprise seven members (SIRT1–7) which are localized to different subcellular compartments.
Xuan Peng, Haiqiang Ni, Baicheng Kuang, Zhiheng Wang, Shuaiheng Hou, Shiqi Gu, Nianqiao Gong   +6 more
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Impact of para aortic lymph node removal on survival following resection for pancreatic adenocarcinoma

BMC Surgery, 2023
Introduction For PDAC patients undergoing resection, it remains unclear whether metastases to the paraaortic lymph nodes (PALN+) have any prognostic significance and whether metastases should lead to the operation not being carried out. Our hypothesis is
Martin Sillesen, Carsten Palnæs Hansen, Stefan Kobbelgaard Burgdorf, Emilie Even Dencker, Paul Suno Krohn, Sophie Louise Gisela Kollbeck, Mogens Tornby Stender, Jan Henrik Storkholm   +7 more
doaj   +1 more source

Longitudinal profiling of gut microbiota dynamics in kidney transplant recipients

Journal of Translational Medicine
Background The gut microbiota undergoes substantial alterations in kidney transplant recipients, which are linked to postoperative complications and renal function recovery. However, the underlying mechanisms of these associations remain unclear. Methods
Weibo Zhong, Runtao Feng, Haoxin Liang, Jianmin Hu, Song Zhou, Ding Liu, Shichao Li, Guorong Liao, Jun Liao, Siqiang Yang, Ya Zhang, Xinyun Xiao, Jun Qian, Hua Chen, Lipei Fan, Min Li, Ming Zhao, Jianrong Chen, Yongguang Liu   +18 more
doaj   +1 more source

Daratumumab followed by tocilizumab for treatment of late antibody-mediated rejection in renal transplant recipients with high or moderate levels of de novo donor-specific antibodies: a pilot study

BMC Nephrology
Background Effective treatment of late antibody-mediated rejection (late AMR) is still an unmet medical need. Clearing donor-specific antibody (DSA) and preventing its rebound is the ideal goal of treatment.
Zhiliang Guo, Rula Sa, Daqiang Zhao, Songxia Li, Hui Guo, Lan Zhu, Gang Chen   +6 more
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Fecal microbiota transplantation alleviates immunosuppressant-associated diarrhea and recurrent urinary tract infection in kidney transplant recipients: a retrospective analysis

Gut Pathogens
Background Immunosuppressant administration subsequent to organ transplantation exerts a substantial influence on gut microbiota composition, thereby affecting patients’ prognosis and quality of life.
Jianmin Hu, Ding Liu, Guorong Liao, Ying Guo, Min Li, Jun Liao, Hua Chen, Song Zhou, Siqiang Yang, Shichao Li, Yongguang Liu, Ming Zhao   +11 more
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Attenuation of Pulmonary Fibrosis by the MyD88 Inhibitor TJ-M2010-5 Through Autophagy Induction in Mice

Biomedicines
Background and Objectives: Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease with few effective treatments. In its pathogenesis, damage-associated molecular patterns are released and recognized by Toll-like receptors (TLRs); all ...
Yang Yang, Zeyang Li, Minghui Zhao, Yuanyuan Zhao, Zhimiao Zou, Yalong Xie, Limin Zhang, Dunfeng Du, Ping Zhou   +8 more
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Investigation of Risk Factors and Development of Clinical Prediction Model for Nocardiosis in Lung Transplant Recipients

Infection and Drug Resistance
Hengyu Zhao,1,* Zhibin Xu,1,* Xiaohua Wang,1,* Yu Xu,1 Yi Lu,1 Jiaqi Chen,1 Qiaoyu Ye,1 Xuan Li,1 Yanhua Wen,2 Chunrong Ju1 1State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease ...
Zhao H, Xu Z, Wang X, Xu Y, Lu Y, Chen J, Ye Q, Li X, Wen Y, Ju C   +9 more
doaj  

Outcomes of patients on chronic kidney replacement therapy admitted to intensive care unit

BMC Nephrology
Background Patients receiving chronic kidney replacement therapy (cKRT) are at high risk of admission to the intensive care unit (ICU), where their management remains challenging.
Sofiane Salhi, Emma Salse, Laurence Lavayssiere, Marie-Béatrice Nogier, Olivier Cointault, Chloé Medrano, Olivier Marion, Amandine Darres, Hélène El Hachem, Clotilde Gaible, Nathalie Longlune, Nassim Kamar, Stanislas Faguer   +12 more
doaj   +1 more source