Results 41 to 50 of about 1,167,376 (291)

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Single-Cell Profiling of Kidney Transplant Recipients With Immunosuppressive Treatment Reveals the Dynamic Immune Characteristics

Frontiers in Immunology, 2021
Kidney transplantation is currently the first choice of treatment for various types of end-stage renal failure, but there are major limitations in the application of immunosuppressive protocols after kidney transplantation.
Yongguang Liu, Xiaoyou Liu, Song Zhou, Ruiquan Xu, Ruiquan Xu, Jianmin Hu, Guorong Liao, Jun Liao, Zefeng Guo, Yuzhu Li, Siqiang Yang, Shichao Li, Hua Chen, Ying Guo, Min Li, Lipei Fan, Liuyang Li, Ming Zhao, Ding Liu   +18 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

HDAC6 inhibition: a significant potential regulator and therapeutic option to translate into clinical practice in renal transplantation

Frontiers in Immunology, 2023
Histone deacetylase 6 (HDAC6), an almost exclusively cytoplasmic enzyme, plays an essential role in many biological processes and exerts its deacetylation-dependent/independent effects on a variety of target molecules, which has contributed to the ...
Qian-qian Zhang, Qian-qian Zhang, Wei-jie Zhang, Wei-jie Zhang, Sheng Chang, Sheng Chang   +5 more
doaj   +1 more source

Organ Transplantation in Argentina

Transplantation, 2018
Argentina is a federal republic located in the southern portion of South America, with a mainland area of 2 780 400 km2. Argentina is the eighth largest country in the world, and the second largest in Latin America. Spanish is the main language; the population has been estimated at 43 847 430 in 2016, (Figure 1).
Gondolesi, Gabriel Eduardo, Bisigniano, Liliana, Bertolotti, Alejandro Mario, Barros Schelotto, Pablo, Raffaele, Pablo   +4 more
openaire   +4 more sources

Attitudes towards organ donation in Malta in the last decade [PDF]

, 2006
Organ transplantation is possibly one of the few cases when even though the medical professionals have the expertise to carry out transplants of certain organs, and even though a person may have financial resources to cover every possible cost, the ...
Lauri, Mary Anne
core  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Organ and tissue donation: Exploring the needs of families

, 2003
Relatives of potential organ donors are the most critical link in maintaining organ availability, as they must express their lack of objection before organ retrieval may take place. The often sudden and unexpected nature of the death of a potential organ
Payne, S., Long-Sutehall, Tracy, Long, T., Sque, Magi, Sque, M., Payne, Sheila   +5 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

An integrated machine learning model enhances delayed graft function prediction in pediatric renal transplantation from deceased donors

BMC Medicine
Background Kidney transplantation is the optimal renal replacement therapy for children with end-stage renal disease; however, delayed graft function (DGF), a common post-operative complication, may negatively impact the long-term outcomes of both the ...
Xiao-You Liu, Run-Tao Feng, Wen-Xiang Feng, Wei-Wei Jiang, Jian-An Chen, Guang-Li Zhong, Chao-Wei Chen, Zi-Jian Li, Jia-Dong Zeng, Ding Liu, Song Zhou, Jian-Min Hu, Guo-Rong Liao, Jun Liao, Ze-Feng Guo, Yu-Zhu Li, Si-Qiang Yang, Shi-Chao Li, Hua Chen, Ying Guo, Min Li, Li-Pei Fan, Hong-Yan Yan, Jian-Rong Chen, Liu-Yang Li, Yong-Guang Liu   +25 more
doaj   +1 more source