Results 1 to 10 of about 61,557 (297)

Immunosuppressant nonadherence profile in kidney transplant recipients and the impact of medication adherence on transplant outcomes

Frontiers in Pharmacology
BackgroundDespite the fact that 1-year graft and recipient survival rates are above 90% in most transplant centers, improving long-term graft survival remains an important challenge.
Zou Zhi-yu, Zou Zhi-yu, Dai Lin-rui, Yu Chen-zhen, Chen Ren-jie, Yu Fei-hong, Chen Song, Chang Sheng, Zhang Wei-jie   +8 more
doaj   +1 more source

A Safety and Tolerability Study of Thin Film Freeze-Dried Tacrolimus for Local Pulmonary Drug Delivery in Human Subjects

Pharmaceutics, 2021
Due to the low and erratic bioavailability of oral tacrolimus (TAC), the long-term survival rate following lung transplantation remained low compared to other solid organs. TAC was reformulated and developed as inhaled formulations by thin film freezing (
Sawittree Sahakijpijarn, Moeezullah Beg, Stephanie M. Levine, Jay I. Peters, Robert O. Williams   +4 more
doaj   +1 more source

A suspected case of a multiple autoimmune syndrome in a poodle dog

Veterinary Medicine and Science, 2022
A 9‐year‐old castrated male poodle dog was presented with icterus, anorexia, and lethargy. The dog was diagnosed with hypothyroidism 1 month before and was treated with levothyroxine.
Dahye Lim, Yunseok Jin, Youngmin Son, Taeho Oh, Seulgi Bae   +4 more
doaj   +1 more source

Recommendations for COVID vaccination for dermatological patients on immunosuppressive/immunomodulatory therapy (IADVL Academy)

Indian Dermatology Online Journal, 2021
Significant proportion of patients with dermatological disorders are on immunosuppressive or immunomodulatory therapy predisposing them to risk of acquisition of COVID-19 infection.
Malathi Munisamy, Bhabani S. T. P. Singh, Deepika Pandhi   +2 more
doaj   +1 more source

Improved Health Outcomes in Patients with Systemic Lupus Erythematosus Following Early Belimumab Initiation Without Prior Immunosuppressant Use: A Real-World Descriptive Study

Rheumatology and Therapy
Introduction Patients with systemic lupus erythematosus (SLE) have variable treatment pathways, including antimalarials, glucocorticoids, immunosuppressants, and/or biologics.
Bernard Rubin, Yan Chen, Karen Worley, Brendan Rabideau, Benson Wu, Rose Chang, Maral DerSarkissian   +6 more
doaj   +1 more source

Microwave – assisted reduction of racemic intermediates potential immunosuppressant

Orbital: The Electronic Journal of Chemistry, 2012
Immunosuppressant are drugs that reduce the immune response, as important in the treatment of autoimmune diseases and rejection attenuators in organ transplants, the structural point of view generally have a high complexity.
Wender A. Silva, João V. Silva, Larissa G. Maciela, Lennine R. Melo, Júlia G. B. Pedreira, Guilherme R. Oliveira   +5 more
doaj   +1 more source

Costimulation blockade and Tregs in solid organ transplantation

Frontiers in Immunology, 2022
Regulatory T cells (Tregs) play a critical role in maintaining self-tolerance and in containing allo-immune responses in the context of transplantation.
Moritz Muckenhuber, Thomas Wekerle, Christoph Schwarz   +2 more
doaj   +1 more source

Pulmonary Embolism after Moderna Vaccination in Kidney Transplant Patients: Two Case Reports and Literature Review

Vaccines, 2022
Currently, the coronavirus disease 2019 (COVID-19) pandemic is still an ongoing and constant medical issue, and with upcoming new variants, vaccinations and boosters remain important.
Wai-Nga Chan, Chih-Shou Chen, Dong-Ru Ho, Yun-Ching Huang, Jian-Hui Lin, Kuo-Tsai Huang, Yu-Liang Liu   +6 more
doaj   +1 more source

Talaromyces marneffei Infection in Systemic Lupus Erythematosus Patients: Report of Two Cases and Review of the Literature

Infection and Drug Resistance, 2020
Jingshan Wei,1 Ye Qiu,1 Wen Zeng,1 Mianluan Pan,1 Jianquan Zhang1,2 1Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, Pepole’s Republic of China; 2Department
Wei J, Qiu Y, Zeng W, Pan M, Zhang J
doaj  

Combination of Dexamethasone and Tofacitinib Reduces Xenogeneic MSC-Induced Immune Responses in a Mouse Model of Alzheimer’s Disease

Biomedicines, 2022
We have recently reported on how transplantation of human mesenchymal stem cells (MSCs) into the mouse parenchyma generated immune responses. To facilitate the clinical translation of MSC-based AD therapy, the safety and efficacy of human derived MSCs ...
Na Kyung Lee, Su Hyeon Myeong, Jung Won Hwang, Jason K. Sa, Hyo Jin Son, Hee Jin Kim, Hyemin Jang, Jong Wook Chang, Duk L. Na   +8 more
doaj   +1 more source