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Immune tolerance

open access: yesZdravniški Vestnik, 2011
BACKGROUND Regulation of human immune system through mechanisms of immune tolerance is an exceptionally important part of the homeostasis that protects the integrity of our organism. Whenever we talk about immune responses, we primarily consider them as an efficient activation of numerous factors enabling our cellular and humoral immunity to protect us
Matjaž Jeras, Urban Švajger
  +6 more sources

The immune response to malaria in utero. [PDF]

open access: yes, 2020
Malaria causes tremendous early childhood morbidity and mortality, providing an urgent impetus for the development of a vaccine that is effective in neonates.
Feeney, Margaret E
core   +1 more source

Tolerance induction in memory CD4 T cells requires two rounds of antigen-specific activation [PDF]

open access: yes, 2014
Autoimmune diseases are driven by immune cells that recognize self-tissues. A major goal for treatment strategies for autoimmune diseases is to turn off or tolerize self-reactive immune cells such as CD4 T cells that coordinate tissue damage in many ...
A. David   +38 more
core   +1 more source

To respond or not to respond - a personal perspective of intestinal tolerance [PDF]

open access: yes, 2018
For many years, the intestine was one of the poor relations of the immunology world, being a realm inhabited mostly by specialists and those interested in unusual phenomena.
A Besredka   +142 more
core   +1 more source

Immunotronics - novel finite-state-machine architectures with built-in self-test using self-nonself differentiation [PDF]

open access: yes, 2002
A novel approach to hardware fault tolerance is demonstrated that takes inspiration from the human immune system as a method of fault detection. The human immune system is a remarkable system of interacting cells and organs that protect the body from ...
Bradley, D.W., Tyrrell, A.M.
core   +2 more sources

CD28 between tolerance and autoimmunity: The side effects of animal models [version 1; referees: 2 approved] [PDF]

open access: yes, 2018
Regulation of immune responses is critical for ensuring pathogen clearance and for preventing reaction against self-antigens. Failure or breakdown of immunological tolerance results in autoimmunity.
A Aruffo   +57 more
core   +2 more sources

Histopathology of the gut in rheumatic diseases [PDF]

open access: yes, 2018
The gastrointestinal tract regulates the trafficking of macromolecules between the environment and the host through an epithelial barrier mechanism and is an important part of the immune system controlling the equilibrium between tolerance and immunity ...
Ciccia F.   +4 more
core   +1 more source

Adaptive immunity in cancer immunology and therapeutics. [PDF]

open access: yes, 2014
Copyright: © the authors; licensee ecancermedicalscience. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution,
Lockley, M, Spurrell, EL
core   +8 more sources

Advancements in immune tolerance [PDF]

open access: yesAdvanced Drug Delivery Reviews, 2008
In recent years, considerable attention has been given to immune tolerance and its potential clinical applications for the treatment of cancers and autoimmune diseases, and the prevention of allo-graft rejection and graft-versus-host diseases. Advances in our understanding of the underlying mechanisms of establishment and maintenance of immune ...
Ping-Ying, Pan   +3 more
openaire   +2 more sources

Intestinal macromolecular transport supporting adaptive immunity [PDF]

open access: yes, 2019
The gastrointestinal tract performs opposing functions of nutrient absorption, barrier maintenance, and the delivery of luminal substances for the appropriate induction of tolerogenic or protective adaptive immunity.
Kulkarni, Devesha H, Newberry, Rodney D
core   +2 more sources

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