Results 31 to 40 of about 1,952,965 (303)

The Epitope-Specific Anti-human CD4 Antibody MAX.16H5 and Its Role in Immune Tolerance

Frontiers in Immunology, 2019
T cell modulation in the clinical background of autoimmune diseases or allogeneic cell and organ transplantations with concurrent preservation of their natural immunological functions (e.g., pathogen defense) is the major obstacle in immunology.
Lilly Stahl, Anna Duenkel, Nadja Hilger, Uta Sandy Tretbar, Stephan Fricke   +4 more
doaj   +1 more source

Changes in Reactivity In Vitro of CD4+CD25+ and CD4+CD25− T Cell Subsets in Transplant Tolerance

Frontiers in Immunology, 2017
Transplant tolerance induced in adult animals is mediated by alloantigen-specific CD4+CD25+ T cells, yet in many models, proliferation of CD4+ T cells from hosts tolerant to specific-alloantigen in vitro is not impaired.
Bruce M. Hall, Catherine M. Robinson, Karren M. Plain, Karren M. Plain, Nirupama D. Verma, Giang T. Tran, Masaru Nomura, Masaru Nomura, Nicole Carter, Nicole Carter, Rochelle Boyd, Rochelle Boyd, Suzanne J. Hodgkinson   +12 more
doaj   +1 more source

Regulatory immune cells in transplantation. [PDF]

, 2012
Immune regulation is fundamental to any immune response to ensure that it is appropriate for the perceived threat to the host. Following cell and organ transplantation, it is essential to control both the innate immune response triggered by the injured ...
Bushell, Andrew, Wood, Kathryn, Bushell, A, Hester, J, Wood, Kathryn J, Andrew Bushell, Joanna Hester, Kathryn J. Wood, Wood, KJ, Hester, Joanna   +9 more
core   +1 more source

Loss of Zbtb32 in NOD mice does not significantly alter T cell responses. [version 2; referees: 2 approved]

F1000Research, 2018
Background: We previously identified the transcriptional regulator Zbtb32 as a factor that can promote T cell tolerance in the Non-Obese Diabetic (NOD) mouse, a model of Type 1 diabetes.
William D. Coley, Yongge Zhao, Charles J. Benck, Yi Liu, Chie Hotta-Iwamura, M. Jubayer Rahman, Kristin V Tarbell   +6 more
doaj   +1 more source

Loss of Zbtb32 in NOD mice does not significantly alter T cell responses. [version 1; referees: 2 approved]

F1000Research, 2018
Background: We previously identified the transcriptional regulator Zbtb32 as a factor that can promote T cell tolerance in the Non-Obese Diabetic (NOD) mouse, a model of Type 1 diabetes.
William D. Coley, Yongge Zhao, Charles J. Benck, Yi Liu, Chie Hotta-Iwamura, M. Jubayer Rahman, Kristin V Tarbell   +6 more
doaj   +1 more source

Intrahepatic CD8+ lymphocyte trapping during tolerance induction using mushroom derived formulations: A possible role for liver in tolerance induction [PDF]

, 2008
AIM: To determine the immunomodulatory effect of Shiitake (a mushroom extract), we tested its effect on liver-mediated immune regulation in a model of immune-mediated colitis. METHODS: Four groups of mice were studied. Colitis was induced by intracolonic
Hershcovici, T., Lidya Zolotarov, Shuvy, M., Mony Shuvy, Cristina Lull-Noguera, Lull-Noguera, C., Tiberiu Hershcovici, Wichers, H.J., Dan Levanon, Harry Wichers, Yaron Ilan, Ofer Danay   +11 more
core   +1 more source

Activity Based Tolerance Allocation (ABTA) – Driving tolerance synthesis by evaluating its global cost [PDF]

, 2009
This paper deals with tolerance allocation driven by an activity based approach. Its main objective is to rationally give a good indicator of the relevance of tolerances values fixed by designers.
MARTIN, Patrick, SIADAT, Ali, DANTAN, Jean-Yves, ETIENNE, Alain   +3 more
core   +1 more source

An Overview of Artificial Immune Systems [PDF]

, 2004
The immune system is highly distributed, highly adaptive, self-organising in nature, maintains a memory of past encounters and has the ability to continually learn about new encounters.
E. Hart, Timmis, Jon, de Castro, Leandro N., L. N. de Castro, Knight, Thomas, Hart, Emma, J. Timmis, T. Knight   +7 more
core   +1 more source

Quantitative Proteomics Identifies TCF1 as a Negative Regulator of Foxp3 Expression in Conventional T Cells

iScience, 2020
Summary: Regulatory T cells are important regulators of the immune system and have versatile functions for the homeostasis and repair of tissues. They express the forkhead box transcription factor Foxp3 as a lineage-defining protein.
Michael Delacher, Melanie M. Barra, Yonatan Herzig, Katrin Eichelbaum, Mahmoud-Reza Rafiee, David M. Richards, Ulrike Träger, Ann-Cathrin Hofer, Alexander Kazakov, Kathrin L. Braband, Marina Gonzalez, Lukas Wöhrl, Kathrin Schambeck, Charles D. Imbusch, Jakub Abramson, Jeroen Krijgsveld, Markus Feuerer   +16 more
doaj   +1 more source

Characterization of lymph node stromal cells during Treg-mediated tolerance [PDF]

, 2013
Solid organs transplantation is therapy of choice for several human diseases. The success of this treatment is determined by the recipientÕs ability to prevent rejection.
Broggi, Maria Anna Sofia
core   +1 more source