Results 11 to 20 of about 1,952,965 (303)
Zdravniški Vestnik, 2011 BACKGROUND Regulation of human immune system through mechanisms of immune tolerance is an exceptionally important part of the homeostasis that protects the integrity of our organism.
Matjaž Jeras, Urban Švajger
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Immune Tolerance Regulation Is Critical to Immune Homeostasis
Journal of Immunology ResearchThe body’s immune response plays a critical role in defending against external or foreign antigens while also preserving tolerance to self-antigens. This equilibrium, referred to as immune homeostasis, is paramount for overall health.
Lei Han +4 more
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Advancements in immune tolerance [PDF]
Advanced Drug Delivery Reviews, 2008 In recent years, considerable attention has been given to immune tolerance and its potential clinical applications for the treatment of cancers and autoimmune diseases, and the prevention of allo-graft rejection and graft-versus-host diseases. Advances in our understanding of the underlying mechanisms of establishment and maintenance of immune ...
Ping-Ying Pan +2 more
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Influence of Innate Immunity on Immune Tolerance [PDF]
Acta Medica Academica, 2020 This review mainly focuses on the mechanisms of peripheral immune tolerance within the perspectives of innate immunity.Healthy immune response requires balanced interaction of the highly specialized elements of immunity within a harmony. In- nate immunity supported by microbial pattern recognition receptors, physical anatomical barriers and soluble ...
Kucuksezer, Umut C +3 more
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Liver-Mediated Adaptive Immune Tolerance
Frontiers in Immunology, 2019 The liver is an immunologically tolerant organ that is uniquely equipped to limit hypersensitivity to food-derived antigens and bacterial products through the portal vein and can feasibly accept liver allografts.
Meijuan Zheng +2 more
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This study investigated the tolerance induction and disruption of immune tolerance as strategies for immune modulation. For induction of immune tolerance, novel monocyte-derived tolerogenic dendritic cells (ItolDCs) were generated, and their ability to modulate the immune system was assessed using <em>in vitro </em>assays in
Dao Nyesiga, Gillian
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Approaches to Establishing Tolerance in Immune Mediated Diseases
Frontiers in Immunology, 2021 The development of rational approaches to restore immune tolerance requires an iterative approach that builds on past success and utilizes new mechanistic insights into immune-mediated pathologies. This article will review concepts that have evolved from
Michelle F. Huffaker +6 more
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Immune Tolerance and Transplantation [PDF]
Seminars in Oncology, 2012 Successful allogeneic hematopoietic stem cell transplantation (HSCT) and solid organ transplantation require development of a degree of immune tolerance against allogeneic antigens. T lymphocytes play a critical role in allograft rejection, graft failure, and graft-versus-host disease (GVHD).
Onder, Alpdogan +1 more
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Frontiers in Immunology, 2022 Immunotherapy for food-allergic patients has been effective in inducing desensitization in some populations, but long-term tolerance has remained an elusive target.
Carolyn H. Baloh +4 more
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Frontiers in Immunology, 2021 CD4+CD25+Foxp3+T cell population is heterogenous and contains three major sub-groups. First, thymus derived T regulatory cells (tTreg) that are naïve/resting. Second, activated/memory Treg that are produced by activation of tTreg by antigen and cytokines.
Bruce M. Hall +17 more
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