Results 91 to 100 of about 90,564 (138)

Alkylation of 1,2,5-Trisubstituted Pyrroles with Donor-Acceptor Cyclopropanes.

Journal of Organic Chemistry
Despite their inherently high nucleophilicity, pyrroles have rarely been explored in Friedel-Crafts-type alkylation reactions with donor-acceptor cyclopropanes (DACs).
Abhijit Gogoi, Kriti Yadav, Bhaskar Kundu, S. K. Das   +3 more
semanticscholar   +1 more source

Copper-Catalyzed Asymmetric Nucleophilic Opening of 1,1,2,2-Tetrasubstituted Donor-Acceptor Cyclopropanes for the Synthesis of α-Tertiary Amines.

Journal of the American Chemical Society
Catalytic asymmetric transformation of donor-acceptor cyclopropanes (DACs) has been proven to be a highly valuable and robust strategy to construct diverse types of enantioenriched molecules.
Shouang Lan, Qinqin Cui, Defu Luo, Siyu Shi, Chengyang He, S. Huang, Chao Xu, Lili Zhao, Jinggong Liu, Cheng-Zhi Gu, Shuang Yang, X. Fang   +11 more
semanticscholar   +1 more source

A Synthetic Route to Functionalized Thiopyran Derivatives via Domino Ring-Opening Cyclization (DROC) of Donor-Acceptor Cyclopropanes with Pyridinium Thiolates.

Journal of Organic Chemistry
An efficient route to 5,6-dihydro-4H-thiopyran derivatives is developed via domino ring-opening cyclization (DROC) of activated donor-acceptor (DA)-cyclopropanes with pyridinium thiolates in the presence of Yb(OTf)3 as the Lewis acid and K2CO3 as the ...
Satysen Yadav, A. K. Sharma, Poulami Mandal, Prabir Manna, M. Ghorai   +4 more
semanticscholar   +1 more source

In(OTf)3-Catalyzed [3 + 2] Cycloaddition Reactions of Donor-Acceptor Cyclopropanes with Thioamides.

Journal of Organic Chemistry
An In(OTf)3-catalyzed [3 + 2] cycloaddition reaction between donor-acceptor cyclopropanes enabled by a single keto acceptor (cyclopropyl ketones) and thioamides has been developed.
Chen-Ying Zhai, Wentao Zhao, Yue Lu, Yan Jiang   +3 more
semanticscholar   +1 more source

Asymmetric Catalytic Reactions of Donor-Acceptor Cyclopropanes.

Angewandte Chemie, 2020
Due to the synergistic "push-pull" effect of vicinal electron-donating and electron-withdrawing groups, donor-acceptor (D-A) cyclopropanes have been recognized as one of the most powerful reagents to generate polyfunctional reactive intermediates after a
Yong Xia, Xiaohua Liu, Xiaoming Feng
semanticscholar   +1 more source

Stereoselective synthesis of functionalized perhydropyrrolo[1,2-b]isoxazoles based on (3 + 2)-annulation of donor-acceptor cyclopropanes and isoxazolines.

Organic and biomolecular chemistry
A stereoselective route to access substituted pyrrolidine cores via Lewis acid catalyzed (3 + 2)-annulation of donor-acceptor cyclopropanes (DACs) and isoxazolines has been developed.
K. V. Potapov, M. A. Novikov, Yaroslav V Kozmenko, P. Solyev, A. Volodin, A. Korlyukov, R. Novikov, Y. V. Tomilov   +7 more
semanticscholar   +1 more source

Organocatalytic Enantioselective Nitro-Vinylcyclopropane-Cyclopentene Rearrangement: Expanding the Reactivity of Donor–Acceptor Cyclopropanes

Synthesis
The catalytic enantioselective rearrangement of nitro-vinylcyclopropylacetaldehydes has been studied using chiral secondary amines as catalysts. The reaction proceeds through the in situ generation of a donor–acceptor cyclopropane, which rearranges to ...
Lorena García, Luisa Carrillo, Efraím Reyes, U. Uria, Liher Prieto, JoseLuis Vicario   +5 more
semanticscholar   +1 more source

Harnessing the Reactivity of Cyclopropenes in the Synthesis of Spiroketals via Putative Generation of Donor-Acceptor Cyclopropanes.

Organic Letters
TMSOTf-mediated 5/6-exo-trig hydroalkoxylation followed by the (3 + 2) cycloaddition cascade reaction of hydroxy cyclopropenes with aldehydes gave an expedient, stereoselective synthesis of [5.5]-and [6.5]-spiroketal derivatives.
Santosh J. Gharpure, Krishna S Gupta, Rakhi Yadav   +2 more
semanticscholar   +1 more source

DBU-Promoted (4 + 1) Annulation of Donor-Acceptor Cyclopropanes with 3-Phenylisoxazol-5(4H)-one: Access to Spiroisoxazol-5(4H)-one Derivatives.

Journal of Organic Chemistry
A DBU-promoted (4 + 1)-annulation reaction between donor-acceptor (D-A) cyclopropanes and 3-phenylisoxazolone has been developed. Using this method, some valuable spiroisoxazol-5(4H)-one derivatives can be obtained easily in good yields.
Wenzhe Cheng, Yuhang Xue, Lizhong Wang, Jiamin Liu, Cunde Wang   +4 more
semanticscholar   +1 more source

Cu(OTf)2 Catalyzed the Reaction of Donor‐Acceptor Cyclopropanes With Salicylaldehyde Phenylhydrazones: Synthesis Polycyclic Tetrahydropyridazines

Journal of Heterocyclic Chemistry
A simple method has been developed to prepare tetrahydro‐5H‐chromeno[4,3‐c]pyridazin‐5‐ones by reacting donor‐acceptor cyclopropane 1,1‐dieters with salicylaldehyde phenylhydrazones in the presence of Cu(OTf)2, yielding moderate results with excellent ...
Zhipin Liu, Lijie Che, J. Pang, Junan Xiao, Xiyan Tang, Chunfang Gan, Jianguo Cui, Yanmin Huang   +7 more
semanticscholar   +1 more source