Results 111 to 120 of about 90,564 (138)

Lewis Acids Catalyzed Regiodivergent N-alkylation of Indazoles with Donor-Acceptor Cyclopropanes

Organic Chemistry Frontiers
N-alkyl Indazoles are highly privileged skeleton in pharmaceutical applications. Generally, N1 and N2-alkyl indazoles represents distinct pharmaceutical and biological activities due to their molecular shape and electrostatic distribution.
Xiaoyan Zhang, Yujiao Xiang, Xiang Zhao, Xin-Yu Zhou, Weiliang Chen, Yungui Peng   +5 more
semanticscholar   +1 more source

Iron-catalyzed cascade C-C/C-O bond formation of 2,4-dienals with donor-acceptor cyclopropanes: access to functionalized hexahydrocyclopentapyrans.

Chemical Communications
Iron-catalyzed cascade C-C and C-O bond formation of 2,4-dienals with donor-acceptor cyclopropanes (DACs) has been developed to furnish hexahydrocyclopentapyrans. Optically active DACs can be coupled stereospecifically (>97% ee).
Manmath Mishra, Kshitiz Verma, Sonbidya Banerjee, T. Punniyamurthy   +3 more
semanticscholar   +1 more source

Formal High-Order Cycloadditions of Donor-Acceptor Cyclopropanes with Cycloheptatrienes.

Angewandte Chemie
Design of various cycloaddition / annulation processes is one of the most intriguing challenges during all time in the development of the donor-acceptor (D-A) cyclopropanes chemistry.
D. Borisov, D. Platonov, Nikita A. Sokolov, Roman A. Novikov, Y. Tomilov   +4 more
semanticscholar   +1 more source

Diastereoselective synthesis of benzazocines by Zn(OTf)2-catalyzed (4+4) cyclocondensation of multisubstituted donor-acceptor cyclopropanes with anthranils.

Chemical Communications
A Zn(OTf)2-catalyzed (4+4) cyclocondensation of anthranils with 2-(trans-1-aroyl-2-arylcyclopropyl)malonates delivers a range of polycyclic benzazocines featuring an oxa-bridged eight-membered ring in excellent yields and with exclusive ...
Xueliang Huang, Gaosheng Yang, Zhuo Chai
semanticscholar   +1 more source

GaCl3‐Promoted Reactions of Donor‐Acceptor Cyclopropanes with Conjugated Diacetylenes

Asian Journal of Organic Chemistry
The reaction of 1,2‐zwitterionic complexes of 2‐arylcyclopropane‐1,1‐dicarboxylates (ACDC), generated using gallium trichloride, with conjugated substituted diacetylenes was studied.
I. A. Borisova, D. Borisov, N. Kolotyrkina, Bo Zhou, Long-Wu Ye, R. A. Novikov, Y. V. Tomilov   +6 more
semanticscholar   +1 more source

Synthesis of thieno[2,3-b]indoles by Cloke-Wilson rearrangement of spiro donor-acceptor cyclopropanes.

Chemical Communications
A one-pot synthesis of thieno[2,3-b]indoles is reported via a Lawesson's reagent-mediated thiocarbonyl Cloke-Wilson rearrangement of spiro donor-acceptor cyclopropyl oxindoles, followed by oxidative aromatization under open-air conditions.
S. Ahashan, Kousik Maji, Syed Ramizul Kabir, Jyotirmayee Dash   +3 more
semanticscholar   +1 more source

Formal C5-Alkylation of Indoles with Donor-Acceptor Cyclopropanes.

Journal of Organic Chemistry
Installing an indole C5 substituent bearing multiple reactive functional groups, either directly via SEAr or any other methods or during indole construction using classic methods, remains challenging due to the inherently low reactivity at this position ...
Kriti Yadav, Abhijit Gogoi, S. K. Das
semanticscholar   +1 more source

Stereodivergent (3 + 2)-cycloaddition of donor-acceptor cyclopropanes and citral imines catalyzed by Yb(NTf2)3/PyBOX.

Organic and biomolecular chemistry
The idea of (3 + 2)-construction of pyrrolidines is realized based on a common natural substrate modified at a single position by functional groups with opposite electronic effects.
P. Sergeev, R. A. Novikov, Y. V. Tomilov
semanticscholar   +1 more source

Asymmetric Catalytic Reactions of Donor–Acceptor Cyclopropanes

Angewandte Chemie - International Edition, 2021
Xiaohua Liu, Xiaoming Feng, Yong Xia
exaly  

Protoglobin‐Catalyzed Formation of cis‐Trifluoromethyl‐Substituted Cyclopropanes by Carbene Transfer

Angewandte Chemie - International Edition, 2023
Xiongyi Huang, Marc Garcia-Borràs, Anders Knight   +2 more
exaly