Results 51 to 60 of about 1,479,892 (242)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Milk sharing: from private practice to public pursuit

International Breastfeeding Journal, 2011
After only six months, a commerce-free internet-based milk-sharing model is operating in nearly 50 countries, connecting mothers who are able to donate breast milk with the caregivers of babies who need breast milk.
Gribble Karleen D, Akre James E, Minchin Maureen   +2 more
doaj   +1 more source

Cow’s Milk Antigens Content in Human Milk: A Scoping Review

Foods, 2022
The functionality of breast milk in terms of immunity is well-known. Despite this, a significant proportion of breastfed infants exhibit sensitization to different potentially allergenic proteins and clinical reactivity (including anaphylaxis) early in ...
Carlos Franco, Cristina Fente, Cristina Sánchez, Alexandre Lamas, Alberto Cepeda, Rosaura Leis, Patricia Regal   +6 more
doaj   +1 more source

THE URGENCY AND IMPLICATION OF BREAST MILK DONOR IN INDONESIA IN MASHLAHAH PERSPECTIVE [PDF]

, 2021
 In Islamic teachings, the issue of breastfeeding is a very important issue to pay attention to, because it can have an impact on the issue of the prohibition of marriage and lineage.
Nofitasari, Khotifatul Defi
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Influence of Holder Pasteurisation on DHA concentrations in human breast milk

, 2008
Human breast milk is universally recognized as the optimal food for term and pre-term infant. In the absence of an adequate supply of breast milk, mothers are offered term breast milk from human milk banks, which collect, process and store milk from ...
L. Marvulli, A. Biasini, MONTI, MICHELA, PATRIGNANI, FRANCESCA, GUERZONI, MARIA ELISABETTA, VANNINI, LUCIA   +5 more
core   +1 more source

Excretion of Dietary Cow's Milk Derived Peptides Into Breast Milk

Frontiers in Nutrition, 2019
Nanoflow-HPLC-tandem mass spectrometry (MS/MS) was used to analyze the peptide fraction of breast milk samples collected from a single non-atopic donor on different days (10 samples) after receiving an oral load of cow's milk (by drinking 200 mL of ...
Gianluca Picariello, Maristella De Cicco, Rita Nocerino, Rita Nocerino, Lorella Paparo, Lorella Paparo, Gianfranco Mamone, Francesco Addeo, Roberto Berni Canani, Roberto Berni Canani, Roberto Berni Canani, Roberto Berni Canani   +11 more
doaj   +1 more source

Gastrointestinal-active oligosaccharides from human milk and functional foods [PDF]

, 2011
Keywords: human milk oligosaccharides (HMOs), galacto-oligosaccharides (GOS), konjac glucomannan (KGM), breast milk, baby feces, gastrointestinal metabolization, blood-group specific conjugates, CE-LIF-MSn Oligosaccharides, as present in human milk ...
Albrecht, S.A.
core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source