Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Global health policies that support the use of banked donor human milk: a human rights issue
International Breastfeeding Journal, 2006 This review examines the role of donor human milk banking in international human rights documents and global health policies. For countries looking to improve child health, promotion, protection and support of donor human milk banks has an important role
Arnold Lois DW
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Human milk‐sharing practices and infant‐feeding behaviours: A comparison of donors and recipients [PDF]
, 2022 Jennifer Peregoy +4 more
openalex +1 more source
FEBS Open Bio, EarlyView.Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel +9 more
wiley +1 more source
Is the innate bio-protection power against human virus the same between males and females? A conclusion based on blood donor data of HTLV-I infection [PDF]
, 2008 Human T-cell leukemia virus type I (HTLV-I) is a retrovirus that causes adult T-cell leukemia. The male-to-female transmission is stronger than the reverse, so the carrier proportion of women is greater than that of men.
Minoru Tabata +3 more
core +1 more source
Emerging trends in 'smart probiotics' : functional consideration for the development of novel health and industrial applications [PDF]
, 2017 The link between gut microbiota and human health is well-recognized and described. This ultimate impact on the host has contributed to explain the mutual dependence between humans and their gut bacteria.
El Hage, Racha +2 more
core +3 more sources
Mothers’ Views on Donor Milk and Human Milk Banks
Pediatrics & Neonatal Biology Open Access, 2022 Aim: The goal of this study is to find out what factors affect mothers’ knowledge and perspectives about wet-nursing and human milk banking. Materials and Methods: This was a cross-sectional, descriptive, and comparative research project. 295 mothers volunteered to take part in the study.
openaire +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
FEBS Open Bio, EarlyView.HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
Eight-year operation status and data analysis of the first human milk bank in East China
International Breastfeeding Journal, 2022 Background Human milk banks (HMBs) are essential facilities for the selection, collection, testing, transportation,storage, and distribution of DHM for special medical needs.
Hu Xiaoshan +6 more
doaj +1 more source
, 2010 This Article examines three traditionally “taboo trades”: (1) the sale of sex, (2) compensated egg donation, and (3) commercial surrogacy. The Article purposely invokes examples in which the compensated provision of goods or services (primarily or ...
Krawiec, Kimberly D.
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