Protein and Immune Component Content of Donor Human Milk in Japan: Variation with Gestational and Postpartum Age [PDF]
, 2023 Miori Tanaka +5 more
openalex +1 more source
Universal Prophylactic Antitumor Vaccination Using Stem Cell Membrane‐Coated Nanoparticles
Advanced Materials, EarlyView.Induced pluripotent stem cell membrane is coated onto adjuvant‐loaded nanoparticle cores to create a universal cancer vaccine. The formulation utilizes oncofetal antigens present on the cell membrane to elicit broadly protective immune responses in vivo.
Nishta Krishnan +10 more
wiley +1 more source
Advanced Sustainable Systems, EarlyView.Inspired from biomedical and pharmaceutical research, crosslinked pectin‐based edible composite coatings are developed for the preservation of butter. The developed coatings exhibit crosslinker calcium chloride dependent preservation response on coated butter over the 60 days storage period. Abstract Given the vulnerability of butter to rancidity there
Orass T. Al‐Ibresam +6 more
wiley +1 more source
Understanding the current and future usage of donor human milk in hospitals: An online survey of UK neonatal units [PDF]
, 2023 Natalie Shenker +5 more
openalex +1 more source
Polymorphic gene conferring susceptibility to insulin-dependent diabetes mellitus typed by ps-resolved FRET on nonamplified genomic DNA [PDF]
arXiv, 2011 This work concerns the identification of the allelic sequences of the DQB1 gene of the human leukocyte antigen system conferring susceptibility to the development of insulin-dependent diabetes mellitus (IDDM) in DNA samples with no need of PCR amplification. Our method is based on the time-resolved analysis of a F\"orster energy-transfer mechanism that
arxiv
D2HGDH Deficiency Regulates Seizures through GSH/Prdx6/ROS‐Mediated Excitatory Synaptic Activity
Advanced Science, EarlyView.Downregulating D‐2‐hydroxyglutarate dehydrogenase (D2HGDH) increases epilepsy susceptibility by altering reactive oxygen species (ROS) levels and synaptic function, contributing to oxidative stress in neurons. The acid calcium‐independent phospholipase A2 (aiPLA2) inhibitor MJ33 restores glutathione reduced/glutathione oxidized balance, reducing ROS ...
Zhijuan Zhang +14 more
wiley +1 more source
Advanced Science, EarlyView.This work presents an injectable polymer‐nanoparticle hydrogel depot platform for delivering multivalent influenza vaccines which induces stronger and more durable immune responses. The technology provides broader protection, including against heterologous and potential pandemic strains (H5N1, H7N9, H9N2), and enhances the effectiveness of commercial ...
Olivia M. Saouaf +7 more
wiley +1 more source
Donor Human Milk: No Longer A Place For Formula in the Neonatal Intensive Care Unit? [PDF]
, 2014 David H. Adamkin, Paula Radmacher
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FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron
Advanced Science, EarlyView.This study aimed to unravel the role of FUS in the loading of functional circRNAs into neuronal sEVs under hypoxic conditions, which involves their aggregations in SGs and specific interaction between the FUS Zf_RanBP domain to regulate circRNA sorting in sEVs.
Jiankun Zang +14 more
wiley +1 more source
The Placenta Regulates Intrauterine Fetal Growth via Exosomal PPARγ
Advanced Science, EarlyView.The placenta expresses much higher levels of PPARγ than fetal adipose tissue. Trophoblastic exosomes transport PPARγ into fetal preadipocytes via fetoplacental circulation and thus regulate adipogenic genes distinct from endogenous PPARγ. Compromised placental PPARγ leads to fetal adipogenesis deficiency and intrauterine growth restriction, reversible ...
Xiaofang Luo +17 more
wiley +1 more source