Results 121 to 130 of about 132,714 (327)

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

Does opening a milk bank in a neonatal unit change infant feeding practices? A before and after study

open access: yesInternational Breastfeeding Journal, 2010
Background Donor human milk banks are much more than simple centers for collection, storage, processing, and distribution of donor human milk, as they cover other aspects and represent a real opportunity to promote and support breastfeeding.
Fernández Cooke Elisa   +6 more
doaj   +1 more source

1337 A study of donor human milk use in Scotland 2020–2021 [PDF]

open access: bronze, 2022
Chloe Thornton   +2 more
openalex   +1 more source

Pasteurized Human Donor Milk as Nutraceutical

open access: yesJournal of Childhood & Developmental Disorders, 2017
Numerous preventive and therapeutic interventions have been designed to decrease mortality and disability in infants. In 2010, 7.6 million children who were less than 5 years of age died worldwide and 4.8 million were attributable to infectious causes.
openaire   +2 more sources

Photothermal Hydrogel with Mn3O4 Nanoparticles Alleviates Intervertebral Disc Degeneration by Scavenging ROS and Regulating Extracellular Matrix Metabolism

open access: yesAdvanced Functional Materials, EarlyView.
The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen   +13 more
wiley   +1 more source

Reconfigurable Nucleic Acid Nanoparticles with Therapeutic RNAi Responses to Intracellular Disease Markers

open access: yesAdvanced Functional Materials, EarlyView.
Many known diseases arise from dysregulated gene expression, and differentially expressed genes can serve as biomarkers to distinguish diseased cells from healthy tissues. In this study, reconfigurable nucleic acid nanoparticles (recNANPs) are introduced that can detect overexpressed cancer biomarkers and subsequently release RNAi inducers to silence ...
Yelixza I. Avila   +7 more
wiley   +1 more source

Human Milk—The Biofluid That Nourishes Infants from the First Day of Life

open access: yesFoods
Human milk is a biofluid with a unique composition among mammalian milks. Besides this milk’s major components, its bioactive compounds, like hormones, immune factors, and oligosaccharides, are unique and important for infant growth and development.
Nikoleta Lugonja   +6 more
doaj   +1 more source

Antibody‐Programmable Bimetallic Nanozymes for Transcriptional Blockade Therapy in HER2/ER‐Positive Breast Cancer

open access: yesAdvanced Functional Materials, EarlyView.
Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao   +8 more
wiley   +1 more source

Fortification of Donor Human Milk for Premature Infants

open access: yesThe FASEB Journal, 2013
Premature infants at risk for metabolic bone disease may need increased minerals for normal bone mineralization, in which case supplementation of donor human milk (DHM) with calcium (Ca), phosphorus (P), and post‐discharge formula (PDF) is common. The bioavailability of these additives has not been proven.
Jonathan C. Allen   +4 more
openaire   +1 more source

Catalytic TiO2 with Self‐Assembled Monolayer for Highly Sensitive, Selective, and Non‐Invasive Monitoring of Sweat L‐Cysteine

open access: yesAdvanced Functional Materials, EarlyView.
A self‐assembled monolayer of 3‐mercaptopropyltrimethoxysilane (MPTS) molecular receptor and titanium oxide‐modified carbon cloth (MPTS/TiO2/CC) was synthesized for the specific detection of sweat L‐cysteine, which is associated with the precision neutrition, cardiovascular system and neuro system.
Xiangjie Chen   +11 more
wiley   +1 more source

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