Results 141 to 150 of about 60,151 (256)

Somatic Evolution of a Germline Antibody Expands its Breadth to Neutralize Early SARS‐CoV‐2 Omicron Variants

Advanced Science, EarlyView.
Engineering of the 148‐germline (148‐GL) antibody reveals a roadmap for overcoming SARS‐CoV‐2 viral escape. By introducing four specific somatic hypermutations, the resulting 148‐M4 variant restores potent neutralization against Omicron BA.1 and BA.4/5.
Huibin Lv, Ziqi Feng, Qi Wen Teo, Chunke Chen, Akshita B. Gopal, Danbi Choi, Timothy J. C. Tan, Yun Sang Tang, Lewis Siu, Armita Nourmohammad, Roberto Bruzzone, Ian A. Wilson, Meng Yuan, Nicholas C. Wu, Chris K. P. Mok   +14 more
wiley   +1 more source

Review of the biological gap between mother's own milk and pasteurized donor milk: implications for intestinal health in preterm infants. [PDF]

Pediatr Res
Sundararajan S, Ma B.
europepmc   +1 more source

Donor milk: current perspectives

, 2014
Francesca Giuliani,1 Ilaria Rovelli,1 Chiara Peila,1 Stefania Alfonsina Liguori,2 Enrico Bertino,1 Alessandra Coscia1 1SCDU Neonatologia, Dipartimento di Scienze Pediatriche e dell'Adolescenza, Università degli Studi di Torino, Torino, Italy; 2SC Neonatologia, Ospedale Maria Vittoria, Torino, Italy Abstract: Mother's own milk
Giuliani,Francesca, Rovelli,Ilaria, Peila,Chiara, Liguori,Stefania Alfonsina, Bertino,Enrico, Coscia,Alessandra   +5 more
openaire   +1 more source

A Global Methane Observation System to Reduce Uncertainty for Anthropogenic and Natural Sources and Sinks for Detecting and Attributing Climate Feedbacks

Advanced Science, EarlyView.
Conceptual illustration of a Global Ecosystem Methane Observing System (GEM‐OS) integrating satellites, aircraft, atmospheric networks, and ecosystem measurements to quantify methane emissions from anthropogenic and natural sources. The multi‐scale observing framework improves source attribution, reduces uncertainty in regional methane budgets, and ...
P. Ciais, S. Peng, J. Chang, F. Li, Q. Zhu, K. Yuan, G. Hugelius, H. Li, Y. Cai, F. Chevallier, K. Tibrewal, E. A. Kort, K. Arndt, J. Watts, B. Buma, N. Besic, P. I. Palmer, H. Cadillo‐Quiroz, E. Euskirchen, M. J. Gondwe, A. Hoyt, R. Jackson, S. Malone, D. Monteverde, S. Natali, M. Ramonet, C. Rey‐Sanchez, L. B. Sagang, E. A. G. Schuur, R. Vargas, R. Varner, Z. Zhang, B. Poulter   +32 more
wiley   +1 more source

A Systematic Review on the Impact of Donor Characteristics and Donor Milk Handling on Infant Health and Growth. [PDF]

Adv Nutr
Klotz D, Bzikowska-Jura A, Giribaldi M, Babiszewska-Aksamit M, Cassidy T, Cavallarin L, Gandino S, Karcz K, Peila C, Smith C, Walczak B, Wesołowska A.   +11 more
europepmc   +1 more source

Experience‐Dependent Reorganization of Hippocampal CA3 Neuronal Ensembles Associates With Memory Generalization

Advanced Science, EarlyView.
Mice can transfer the learned rule of spatial working memory to guide similar but novel tasks. Hippocampal CA3 populational activity dynamically reorganize during memory generalization, shifting from task‐specific to generalized coding over testing days. Sparse yet redundant neural representations of CA3 enable rule transfer and cognitive map formation,
Da Song, Zilu Zhu, Yujun Deng, Yujie Song, Hui Li, Junjun Ni, Zhenzhen Quan, Yan Yan, Hong Qing   +8 more
wiley   +1 more source

High-Temperature Short-Time and Holder Pasteurization of Donor Milk: Impact on Milk Composition. [PDF]

Life (Basel), 2021
Escuder-Vieco D, Rodríguez JM, Espinosa-Martos I, Corzo N, Montilla A, García-Serrano A, Calvo MV, Fontecha J, Serrano J, Fernández L, Pallás-Alonso CR.   +10 more
europepmc   +1 more source

Targeted Degradation of Picornaviral 3C Protease via PROTACs Confers High Barrier to Viral Resistance and Broad‐Spectrum Antiviral Activity

Advanced Science, EarlyView.
This study reports D34 as the first PROTAC degrader that targets the 3C protease of picornaviruses. D34 effectively degrades EV71 3C protease via the ubiquitin‐proteasome pathway. More importantly, D34 exhibits a high resistance barrier and shows broad‐spectrum antiviral activity against multiple picornaviruses, highlighting its potential as a novel ...
Weilong Deng, Junyu Chen, Yingyue Pang, Yuanyuan Zhang, Siqian Chen, Guoliang You, Xiaoman Tian, Zhongxin Xu, Jing Wang, Luqing Shang   +9 more
wiley   +1 more source

Freeze-Dried Donor Milk for Fortification of Mother's Own Milk in Preterm Infants: A Preliminary Observational Study. [PDF]

Nutrients
Rochow N, Weiss GA, Knab K, Prothmann I, Schäfer S, Zimmermann JL, Meis A, Lohmüller-Weiß S, Simon K, Schäfer S, Welsch J, Fusch C.   +11 more
europepmc   +1 more source

Erratum: Neurodevelopmental Outcome in Very Low Birth Weight Infants Exposed to Donor Milk. [PDF]

Am J Perinatol, 2022
Patra K, Greene MM, Tobin G, Casini G, Esquerra-Zwiers AL, Meier PP, Patel AL.   +6 more
europepmc   +1 more source