Results 111 to 120 of about 577,472 (296)

One Year Outcomes Following Transplantation with COVID-19-Positive Donor Hearts: A National Database Cohort Study

Journal of Cardiovascular Development and Disease
The current understanding of the safety of heart transplantation from COVID-19+ donors is uncertain. Preliminary studies suggest that heart transplants from these donors may be feasible.
Stanley B. Wolfe, Ruby Singh, Dane C. Paneitz, Seyed Alireza Rabi, Chijioke C. Chukwudi, Richa Asija, Eriberto Michel, Asvin M. Ganapathi, Asishana A. Osho   +8 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Outcomes of Kidney Transplantation from Deceased Donors with Severe Acute Kidney Injury (AKIN Stage 3): A Preliminary Single-Centre Analysis

Medical Sciences
Background: The shortage of donor kidneys has prompted interest in using organs from donors with severe acute kidney injury (AKI), but robust data on outcomes from donors with AKIN stage 3 remain limited. Methods: This single-centre, retrospective cohort
Juan A. Encarnación, Elisabeth Coll, Clara Manso, Santiago Llorente, Francisco Morales, Isabel Saura, Pedro López-Cubillana, Pablo Luis Guzman Martínez-Valls, Gloria Martínez, Isabel De la Fuente, Enrique Cárdenas, Jose L. Alonso-Romero, Paula Ruiz, José Moya, Beatriz Domínguez-Gil, Mario Royo-Villanova   +15 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

An evaluation of the prevalence and causes of blood donor deferral in Lagos state, Nigeria

Discover Public Health
Background Blood transfusion safety relies on thorough donor eligibility assessments that lead to the deferral of individuals who do not meet established criteria.
Olufemi Abiola Oyedeji, Shadrach Chidi Edenyi, Olusola Festus Olowoselu, Ademola Samson Adewoyin, Nosimot Omolola Davies, Bodunrin Ibitola Osikomaiya   +5 more
doaj   +1 more source

Program of Uncontrolled Donation After Circulatory Death as Potential Solution to the Shortage of Organs: A Canadian Single-Center Retrospective Cohort Study

Open Access Emergency Medicine, 2022
Frederick D’Aragon,1,2 Olivier Lachance,1 Vincent Lafleur,1 Ivan Ortega-Deballon,3,4 Marie-Helene Masse,5 Gabrielle Trepanier,6 Daphnee Lamarche,1 Marie-Claude Battista5 1Department of Anesthesiology, Faculty of Medicine and Health Sciences Université de
D'Aragon F, Lachance O, Lafleur V, Ortega-Deballon I, Masse MH, Trepanier G, Lamarche D, Battista MC   +7 more
doaj  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Identification of embryonic yield-related serum biomarkers using proteomic analysis in ovine superovulation

Frontiers in Veterinary Science
Superovulation is an efficient technology for the propagation of excellent livestock. Blood proteins other than reproductive hormones might be related to the outcome of superovulation.
Xiaohu Su, Yijing Zhu, Zirong Guo, Shuang Qiu, Quan Liu, Chao Bian, Liqiang Chen, Hideaki Yamashiro, Guangnan Liu, Zhanwen Zhang, Liguo Zhang, Bin Tong   +11 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Selecting Donor Recipients [PDF]

Biology of Blood and Marrow Transplantation, 2009
openaire   +2 more sources