Results 101 to 110 of about 584,120 (299)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Donor-Recipient Mismatch in Lung Transplantation: The Role of Graft Sizing in Clinical Outcomes

Transplant International
Lung transplantation is a life-saving procedure for end-stage lung diseases. Size matching is critical in the donor-recipient selection process. This retrospective study analyzed 146 patients who underwent lung transplantation between 2013 and 2023 ...
Chiara Catelli, Chiara Catelli, Miriana D’Alessandro, Andrea Lloret Madrid, Antonella Fossi, Federico Franchi, Federico Franchi, David Bennett, Piero Paladini, Piero Paladini, Elena Bargagli, Elena Bargagli, Luca Luzzi, Luca Luzzi   +13 more
doaj   +1 more source

The Geographical Allocation Pattern of Spanish Official Development Assistance [PDF]

The geographical allocation of Spanish aid has been little studied, despite the fact that it is unusually concentrated on middle-income countries. This paper sets out a model of Spanish ODA policy based on an integrated approach reflecting recipient ...
Sergio Tezanos Vazquez (ICEI and QEH)
core  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Eelgrass Habitat Creation in Nantucket Harbor, Massachusetts [PDF]

, 2012
In response to eelgrass habitat losses associated with development and marine activities in and around Nantucket Harbor, a plan to restore a meadow by transplanting eelgrass to previously vegetated areas was developed in conjunction with the Nantucket ...
Burdick, David M, Moore, Gregg, Peter, Chris   +2 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Use of extended criteria donor cardiac allografts after multiple offers is associated with inferior post-transplant outcomes

JHLT Open
Purpose: Extended criteria donor (ECD) cardiac allografts have increased the donor pool for heart transplant (HT). The effect of donor sequence number (DSN), number of times a recipient’s donor organ has been offered prior to acceptance, on post-ECD HT ...
Cindy Song, MD, Amit Iyengar, MD, MSE, David Rekhtman, MD, Michaela Asher, MPhil, Max Shin, MD, Noah Weingarten, MD, Omar Toubat, MD, PhD, Mauer Biscotti, MD, Marisa Cevasco, MD, MPH   +8 more
doaj   +1 more source

Donor Selection

, 2017
AbstractAllogeneic haematopoietic stem cell transplant (HSCT) is the treatment of choice for a variety of malignant and non-malignant disorders. The aim of HSCT is to replace the patient’s haematopoiesis with that taken from a donor, and a prerequisite is the identification of a suitable donor.
openaire   +1 more source

Donor selection in the modern era

Annals of Cardiothoracic Surgery, 2018
The growing disparity between the supply of donor hearts for transplantation and the demand for such organs has led to liberalization of the criteria for donor heart acceptance over the past few decades. The upper age limit and size restrictions for donor heart acceptance continue to be revised and hearts are being routinely used from donors with left ...
openaire   +3 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source