Results 1 to 10 of about 23,389 (155)

KIR AA individuals possess strong inhibitory KIR alleles alongside HLA ligands that are protective against leukemia in the Chinese population [PDF]

open access: yesFrontiers in Genetics
IntroductionThe killer-cell immunoglobulin-like receptor (KIR) gene cluster exhibits complicated diversity in haplotype content, copy-number variation (CNV), and allelic polymorphism.
Zhihui Deng   +12 more
doaj   +2 more sources

KIR And HLA Haplotype Analysis in a Family Lacking The KIR 2DL1-2DP1 Genes [PDF]

open access: yesBalkan Journal of Medical Genetics, 2015
The killer cell immunoglobulin-like receptor (KIR) gene cluster exhibits extensive allelic and haplotypic diversity that is observed as presence/absence of genes, resulting in expansion and contraction of KIR haplotypes and by allelic variation of ...
Vojvodić Svetlana   +1 more
doaj   +3 more sources

Linkage disequilibrium organization of the human KIR superlocus: implications for KIR data analyses [PDF]

open access: yesImmunogenetics, 2010
An extensive family-based study of linkage disequilibrium (LD) in the killer cell immunoglobulin-like receptors (KIR) cluster was performed. We aimed to describe the LD structure in the KIR gene cluster using a sample of 418 founder haplotypes identified by segregation in a group of 106 families from Northern Ireland.
Anne Cambon-Thomsen   +2 more
exaly   +6 more sources

KIR genotype distribution among patients with multiple myeloma: Higher prevalence of KIR 2DS4 and KIR 2DS5 genes

open access: yesMeta Gene, 2014
Natural killer (NK) cells possess an antitumor activity against multiple myeloma cells proven by the susceptibility of plasmocytes to NK lysis. In the early stage of MM, the killing of MM cells is mediated by natural cytotoxicity receptors (NRC) and NKG2D-dependent pathway, while in the late stage, NK cells lose their killing potential against MM cells
Rami Mahfouz
exaly   +3 more sources

Кір [Kir]

open access: yes, 2013
КІР – назва групи природних бітумів , що утворюються в результаті вивітрювання в зоні виходів легких метанових і нафтенових нафт. Залежно від складу та глибини вивітрювання нафт колір К. змінюється від темно-коричневого до чорного. Густина 0,96–1,2. Розчинний в орган. розчинниках ⚠️ Цей запис містить лише бібліографічні метадані.
  +12 more sources

De Novo Assembly of Plasmodium knowlesi Genomes From Clinical Samples Explains the Counterintuitive Intrachromosomal Organization of Variant SICAvar and kir Multiple Gene Family Members

open access: yesFrontiers in Genetics, 2022
Plasmodium knowlesi, a malaria parasite of Old World macaque monkeys, is used extensively to model Plasmodium biology. Recently, P. knowlesi was found in the human population of Southeast Asia, particularly Malaysia. P.
Damilola R. Oresegun   +8 more
doaj   +1 more source

Low number of KIR ligands in lymphoma patients favors a good rituximab-dependent NK cell response

open access: yesOncoImmunology, 2021
The antibody-dependent cellular cytotoxicity (ADCC) effector function of natural killer (NK) cells is one of the known mechanisms of action for rituximab-based anti-cancer immunotherapy.
Dhon Roméo Makanga   +15 more
doaj   +1 more source

Killer cell immunoglobulin-like receptor alleles influence susceptibility to occult hepatitis B infection in West African population

open access: yesJournal of Public Health in Africa, 2023
Occult hepatitis B infection (OBI) is a public health problem in Burkina Faso. OBI represents a risk factor for the development of cirrhosis and hepatocellular carcinoma (HCC).
Momeiyi M. Bazie   +13 more
doaj   +1 more source

Study on relationship between platelet transfusion efficacy and KIR-HLA receptor-ligand compatibility

open access: yesZhongguo shuxue zazhi, 2023
Objective To study the correlation between platelet transfusion efficacy and KIR receptor-HLA ligand. Methods Thirty-three leukemia patients with positive HLA antibody were tested for cross-matching with donor platelets.
Yu HAN   +12 more
doaj   +1 more source

Hydrodynamic Aspects of Staggered Spoilers fitted Subsea Pipelines [PDF]

open access: yesPort Said Engineering Research Journal, 2017
Subsea pipelines are affected with many surrounding challenges. One of these challenges is the current-induced hydrodynamic stresses which affect the pipeline throughout its life span.
Ahmed El Shafei   +3 more
doaj   +1 more source

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