Results 11 to 20 of about 38,491 (220)
Molecular determinant-based typing of KIR alleles and KIR ligands [PDF]
Clinical Immunology, 2011 Killer cell immunoglobulin-like receptors (KIRs) regulate NK cell function. KIRs and their HLA ligands are highly polymorphic in nature with substantial allelic polymorphism. At present, there is a lack of an expedient method for KIR and HLA allele typing with relevant functional information.
Rafijul, Bari +6 more
openaire +3 more sources
Drug Design, Development and Therapy, 2018 Yayi He,1,2,* Sangtian Liu,1,* Jane Mattei,3 Paul A Bunn Jr,2 Caicun Zhou,1 Daniel Chan2 1Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai ...
He YY +5 more
doaj +1 more source
Treatment-Free Remission in Chronic Myeloid Leukemia: Toward Precision and Personalized Approaches to Functional Cure. [PDF]
Cancer SciImmune surveillance of residual leukemic stem cells after tyrosine kinase inhibitor discontinuation involves coordinated NK‐cell, CTL, Treg, pDC, and neutrophil activity that predicts treatment‐free remission, while exhausted CTLs and Treg expansion predict relapse in chronic myeloid leukemia.
Ureshino H, Kimura S.
europepmc +2 more sources
Hydrodynamic Aspects of Staggered Spoilers fitted Subsea Pipelines [PDF]
Port Said Engineering Research Journal, 2017 Subsea pipelines are affected with many surrounding challenges. One of these challenges is the current-induced hydrodynamic stresses which affect the pipeline throughout its life span.
Ahmed El Shafei +3 more
doaj +1 more source
Killer-Cell Immunoglobulin-like Receptor Diversity in an Admixed South American Population
Cells, 2022 Natural Killer (NK) cells are innate immune cells that mediate antiviral and antitumor responses. NK cell activation and induction of effector functions are tightly regulated by the integration of activating and inhibitory receptors such as killer ...
Marlon Castrillon +4 more
doaj +1 more source
Autologous and allogeneic HLA KIR ligand environments and activating KIR control KIR NK‐cell functions [PDF]
European Journal of Immunology, 2008 AbstractNK‐cell function is regulated by a balance between inhibitory and activating killer cell immunoglobulin‐like receptors (KIR) that specifically recognize HLA class I molecules. Using KIR‐specific mAb to discriminate between KIR2DS1 and KIR2DL1 receptors, we show that KIR2DS1+ NK cells are C2‐alloreactive only from C2− individuals.
Morvan, Maelig +11 more
openaire +3 more sources
Neuromodulation: Technology at the Neural Interface, EarlyView., 2021 Abstract Objectives Hypoglossal nerve stimulation is an effective treatment option for obstructive sleep apnea (OSA) in positive airway pressure therapy failure. Nonetheless, data regarding the functional effect of modifying stimulation parameters within each electrode configuration are limited.
Armin Steffen +4 more
wiley +1 more source
KiR-predicted top ‘informative’ kinases for DOX plus NaB condition.
, 2023 KiR-predicted top ‘informative’ kinases for DOX plus NaB condition.
Songli Zhu (14930907) +8 more
core +1 more source
Analysis of Killer Immunoglobulin-Like Receptor Genes in Colorectal Cancer
Cells, 2020 Natural killer cells (NK cells) play a major role in the immune response to cancer. An important element of NK target recognition is the binding of human leucocyte antigen (HLA) class I molecules by killer immunoglobulin-like receptors (KIRs). Colorectal
Roberto Diaz-Peña +5 more
doaj +1 more source
KiR-predicted kinase inhibitor responses for DOX plus NaB condition.
, 2023 KiR-predicted kinase inhibitor responses for DOX plus NaB condition.
Songli Zhu (14930907) +8 more
core +1 more source