Results 11 to 20 of about 21,873 (185)

KIR And HLA Haplotype Analysis in a Family Lacking The KIR 2DL1-2DP1 Genes [PDF]

Balkan Journal of Medical Genetics, 2015
Abstract The killer cell immunoglobulin-like receptor (KIR) gene cluster exhibits extensive allelic and haplotypic diversity that is observed as presence/absence of genes, resulting in expansion and contraction of KIR haplotypes and by allelic variation of individual KIR genes.
Vojvodić Svetlana, Ademović-Sazdanić D.   +1 more
openaire   +3 more sources

De Novo Assembly of Plasmodium knowlesi Genomes From Clinical Samples Explains the Counterintuitive Intrachromosomal Organization of Variant SICAvar and kir Multiple Gene Family Members

Frontiers in Genetics, 2022
Plasmodium knowlesi, a malaria parasite of Old World macaque monkeys, is used extensively to model Plasmodium biology. Recently, P. knowlesi was found in the human population of Southeast Asia, particularly Malaysia. P.
Damilola R. Oresegun, Peter Thorpe, Ernest Diez Benavente, Susana Campino, Fauzi Muh, Robert William Moon, Taane Gregory Clark, Taane Gregory Clark, Janet Cox-Singh   +8 more
doaj   +1 more source

Low number of KIR ligands in lymphoma patients favors a good rituximab-dependent NK cell response

OncoImmunology, 2021
The antibody-dependent cellular cytotoxicity (ADCC) effector function of natural killer (NK) cells is one of the known mechanisms of action for rituximab-based anti-cancer immunotherapy.
Dhon Roméo Makanga, Maxime Jullien, Gaëlle David, Nolwenn Legrand, Catherine Willem, Léa Dubreuil, Alexandre Walencik, Cyrille Touzeau, Thomas Gastinne, Benoit Tessoulin, Steven Le Gouill, Béatrice Mahé, Katia Gagne, Patrice Chevallier, Béatrice Clemenceau, Christelle Retière   +15 more
doaj   +1 more source

Killer cell immunoglobulin-like receptor alleles influence susceptibility to occult hepatitis B infection in West African population

Journal of Public Health in Africa, 2023
Occult hepatitis B infection (OBI) is a public health problem in Burkina Faso. OBI represents a risk factor for the development of cirrhosis and hepatocellular carcinoma (HCC).
Momeiyi M. Bazie, Florencia W. Djigma, Mahamoudou Sanou, Pegdwendé A. Sorgho, Abdoul K. Ouattara, Dorcas Obiri-Yeboah, Nadege Kapieko, Herman K. Sombie, Prosper Bado, Edwige T. Yelemkoure, Isabelle T. Kiendrebeogo, Marius B. Nagalo, Albert T. Yonli, Jacques Simpore   +13 more
doaj   +1 more source

Study on relationship between platelet transfusion efficacy and KIR-HLA receptor-ligand compatibility

Zhongguo shuxue zazhi, 2023
Objective To study the correlation between platelet transfusion efficacy and KIR receptor-HLA ligand. Methods Thirty-three leukemia patients with positive HLA antibody were tested for cross-matching with donor platelets.
Yu HAN, Fan YANG, Lixin JIAO, Lingling LIU, Jianghong YU, Tingting NIE, Xin LIU, Rixin BAI, Xu YANG, Ying CHEN, Yanfei LI, Kaiye LI, Xiaotang YU   +12 more
doaj   +1 more source

Hydrodynamic Aspects of Staggered Spoilers fitted Subsea Pipelines [PDF]

Port Said Engineering Research Journal, 2017
Subsea pipelines are affected with many surrounding challenges. One of these challenges is the current-induced hydrodynamic stresses which affect the pipeline throughout its life span.
Ahmed El Shafei, Mohamed Kotb, Amr Hassan, Khalid Saqr   +3 more
doaj   +1 more source

<i>KIR AA</i> individuals possess strong inhibitory <i>KIR</i> alleles alongside HLA ligands that are protective against leukemia in the Chinese population. [PDF]

Front Genet
IntroductionThe killer-cell immunoglobulin-like receptor (KIR) gene cluster exhibits complicated diversity in haplotype content, copy-number variation (CNV), and allelic polymorphism.
Deng Z, Zhen J, Li Y, Liang S, Zhang M, Cai S, Jiang R, Yang Z, Yu Q, Wang J, Liu J.   +10 more
europepmc   +2 more sources

Killer-Cell Immunoglobulin-like Receptor Diversity in an Admixed South American Population

Cells, 2022
Natural Killer (NK) cells are innate immune cells that mediate antiviral and antitumor responses. NK cell activation and induction of effector functions are tightly regulated by the integration of activating and inhibitory receptors such as killer ...
Marlon Castrillon, Nancy D. Marin, Amado J. Karduss-Urueta, Sonia Y. Velasquez, Cristiam M. Alvarez   +4 more
doaj   +1 more source

The KIR repertoire of a West African chimpanzee population is characterized by limited gene, allele, and haplotype variation

Frontiers in Immunology, 2023
IntroductionThe killer cell immunoglobulin-like receptors (KIR) play a pivotal role in modulating the NK cell responses, for instance, through interaction with major histocompatibility complex (MHC) class I molecules.
Natasja G. de Groot, Corrine M.C. Heijmans, Marit K.H. van der Wiel, Jesse Bruijnesteijn, Ronald E. Bontrop, Ronald E. Bontrop   +5 more
doaj   +1 more source

Analysis of Killer Immunoglobulin-Like Receptor Genes in Colorectal Cancer

Cells, 2020
Natural killer cells (NK cells) play a major role in the immune response to cancer. An important element of NK target recognition is the binding of human leucocyte antigen (HLA) class I molecules by killer immunoglobulin-like receptors (KIRs). Colorectal
Roberto Diaz-Peña, Patricia Mondelo-Macía, Antonio José Molina de la Torre, Rebeca Sanz-Pamplona, Víctor Moreno, Vicente Martín   +5 more
doaj   +1 more source