Neuromodulation: Technology at the Neural Interface, EarlyView., 2021 Abstract Objectives Hypoglossal nerve stimulation is an effective treatment option for obstructive sleep apnea (OSA) in positive airway pressure therapy failure. Nonetheless, data regarding the functional effect of modifying stimulation parameters within each electrode configuration are limited.
Armin Steffen +4 more
wiley +1 more source
Verminderung der bFGF-vermittelten Endothelzellproliferation durch nikotininduzierte Reduktion des endothelialen Einwärtsgleichrichter Kaliumstromes [PDF]
, 2002 Einwärtsgleichrichter Kaliumkanäle (KIR-Kanäle) steuern mit ihren die Zelle dominierenden Ionenströmen das Ruhepotential der Endothelzellen. Über die Steuerung des Ruhepotentials haben sie auch einen wesentlichen Einfluß auf die intrazelluläre ...
Scharbrodt, Wolfram
core +3 more sources
Simple models of the chemical field around swimming plankton [PDF]
, 2010 Background. Cervical cancer is the fourth most common cancer in women, and we recently reported human leukocyte antigen (HLA) alleles showing strong associations with cervical neoplasia risk and protection.
Bao, Xiao, +35 more
core +2 more sources
Impact of killer-immunoglobulin-like receptor and human leukocyte antigen genotypes on the efficacy of immunotherapy in acute myeloid leukemia [PDF]
, 2017 Interactions between killer-immunoglobulin-like receptors (KIRs) and their HLA class I ligands are instrumental in natural killer (NK) cell regulation and protect normal tissue from NK cell attack.
Aurelius, J. +12 more
core +1 more source
CO2-dependent opening of an inwardly rectifying K+ channel [PDF]
, 2011 CO2 chemosensing is a vital function for the maintenance of life that helps to control acid–base balance. Most studies have reported that CO2 is measured via its proxy, pH. Here we report an inwardly rectifying channel, in outside-out excised patches
Huckstepp, Robert T. R., Dale, Nicholas
core +1 more source
Molecular determinant-based typing of KIR alleles and KIR ligands [PDF]
Clinical Immunology, 2011 Killer cell immunoglobulin-like receptors (KIRs) regulate NK cell function. KIRs and their HLA ligands are highly polymorphic in nature with substantial allelic polymorphism. At present, there is a lack of an expedient method for KIR and HLA allele typing with relevant functional information.
Rafijul, Bari +6 more
openaire +2 more sources
Mechanisms of Copy Number Variation and Hybrid Gene Formation in the KIR Immune Gene Complex [PDF]
, 2011 The fine-scale structure of the majority of copy number variation (CNV) regions remains unknown. The killer immunoglobulin receptor (KIR) gene complex exhibits significant CNV.
Carrington, Mary +8 more
core +1 more source
Killer Immunoglobulin-Like Receptor Allele Determination Using Next-Generation Sequencing Technology
Frontiers in Immunology, 2017 The impact of natural killer (NK) cell alloreactivity on hematopoietic stem cell transplantation (HSCT) outcome is still debated due to the complexity of graft parameters, HLA class I environment, the nature of killer cell immunoglobulin-like receptor ...
Bercelin Maniangou +17 more
doaj +1 more source
Killer-cell Immunoglobulin-like Receptor gene linkage and copy number variation analysis by droplet digital PCR. [PDF]
, 2014 The Killer-cell Immunoglobulin-like Receptor (KIR) gene complex has considerable biomedical importance. Patterns of polymorphism in the KIR region include variability in the gene content of haplotypes and diverse structural arrangements.
Holland, Martin J +5 more
core +3 more sources
Alexandria Engineering Journal, 2020 The present paper introduces a theoretical study carried out to investigate the effect of shaft lateral misalignment on the dynamic characteristics of labyrinth seals under stationary conditions.
E. Saber, Khaled M. Abdou, R. Afify
doaj +1 more source