Results 21 to 30 of about 21,873 (185)

The Evolutionary Arms Race between Virus and NK Cells: Diversity Enables Population-Level Virus Control

Viruses, 2019
Viruses and natural killer (NK) cells have a long co-evolutionary history, evidenced by patterns of specific NK gene frequencies in those susceptible or resistant to infections.
Sarah K. A. Savoy, Jeanette E. Boudreau   +1 more
doaj   +1 more source

Investigation of KIR/HLA relationship and other clinical variables after T-cell-replete haploidentical bone marrow transplantation in patients with acute myeloid leukemia (AML)

BMC Immunology, 2023
Background KIR/HLA mismatch in hematopoietic stem cell transplantation (HSCT), particularly in patients with acute myeloid leukemia (AML), was related to decreased recurrence rates, improved engraftment, and a reduction in graft-versus-host disease ...
Tahereh Bakhtiari, Mohammad Ahmadvand, Marjan Yaghmaie, Alireza Sadeghi, Seied Asadollah Mousavi, Tahereh Rostami, Mazdak Ganjalikhani-Hakemi   +6 more
doaj   +1 more source

KIR Variation in Iranians Combines High Haplotype and Allotype Diversity With an Abundance of Functional Inhibitory Receptors

Frontiers in Immunology, 2020
Natural killer (NK) cells are innate lymphocytes that eliminate infected and transformed cells. They discriminate healthy from diseased tissue through killer cell Ig-like receptor (KIR) recognition of HLA class I ligands.
Claudia Alicata, Elham Ashouri, Elham Ashouri, Elham Ashouri, Elham Ashouri, Neda Nemat-Gorgani, Neda Nemat-Gorgani, Neda Nemat-Gorgani, Lisbeth A. Guethlein, Lisbeth A. Guethlein, Wesley M. Marin, Sudan Tao, Sudan Tao, Lorenzo Moretta, Jill A. Hollenbach, John Trowsdale, James A. Traherne, Abbas Ghaderi, Peter Parham, Peter Parham, Paul J. Norman, Paul J. Norman, Paul J. Norman   +22 more
doaj   +1 more source

Family-based Association Study of Killer Cell Immunoglobulin-Like Receptor Genes with Leukemia

Acta Medica Bulgarica, 2019
NK cell function is controlled by the cell expression of killer immunoglobulin-like receptors (KIRs) and their ligation with the corresponding HLA ligands.
Varbanova V., Mihaylova S., Naumova E., Cotoc C., Mihaylova A.   +4 more
doaj   +1 more source

Distribution of killer cell immunoglobulin-like receptor (KIR) genes in a large, multi-centre cohort of Chinese donors

Annals of Human Biology, 2021
Background The killer cell immunoglobulin-like receptor (KIR), which mediates the killing function of NK cells, is an attractive candidate for adoptive cellular therapy.
Min He, Zhong-zheng Zheng, Qing-qing He, Dai-yang Li, Kuan-zhen Liao, Lin An, Qi Weng, Ning-juan Wang, Li-ping Wang, Qin Sun, Jian Wang, Pei-li Xiao, Ke-ming Du, Ming Jiang   +13 more
doaj   +1 more source

Steady state characteristics and stability limits of oil lubricated journal bearings using titanium dioxide nanoparticles as lubricant additives

Results in Engineering, 2023
The current work is presented to investigate the impact of titanium dioxide (TiO2) nanoparticle volume fraction and the nanoparticle aggregate sizes on the steady state characteristics and stability limits of journal bearings.
H. Awad, Khaled M. Abdou, E. Saber
doaj   +1 more source

Killer Immunoglobulin-Like Receptor Allele Determination Using Next-Generation Sequencing Technology

Frontiers in Immunology, 2017
The impact of natural killer (NK) cell alloreactivity on hematopoietic stem cell transplantation (HSCT) outcome is still debated due to the complexity of graft parameters, HLA class I environment, the nature of killer cell immunoglobulin-like receptor ...
Bercelin Maniangou, Bercelin Maniangou, Nolwenn Legrand, Nolwenn Legrand, Mehdi Alizadeh, Ulysse Guyet, Catherine Willem, Catherine Willem, Gaëlle David, Gaëlle David, Eric Charpentier, Alexandre Walencik, Christelle Retière, Christelle Retière, Katia Gagne, Katia Gagne, Katia Gagne, Katia Gagne   +17 more
doaj   +1 more source

Expression patterns of killer cell immunoglobulin-like receptors (KIR) of NK-cell and T-cell subsets in Old World monkeys. [PDF]

PLoS ONE, 2013
The expression of killer cell immunoglobulin-like receptors (KIR) on lymphocytes of rhesus macaques and other Old World monkeys was unknown so far.
Meike Hermes, Christina Albrecht, Annette Schrod, Markus Brameier, Lutz Walter   +4 more
doaj   +1 more source

Pengembangan Aplikasi Pencari Fasilitator KIR (Kelompok Ilmiah Remaja) Kelompok Peneliti Muda Universitas Negeri Jakarta (KPM UNJ) Berbasis Web

Risenologi, 2018
Kelompok Ilmiah Remaja (KIR) adalah kelompok remaja yang masih berstatus siswa yang melakukan serangkaian kegiatan ilmiah berupa percobaan sederhana atau penulisan yang menghasilkan suatu hasil yang disebut karya ilmiah.
Fahrul Kurniawan, Rahma Rosaliana Saraswati, Gerald Fransiscus   +2 more
doaj   +1 more source

New Screening System for Selective Blockers of Voltage-Gated K+ Channels Using Recombinant Cell Lines Dying Upon Single Action Potential

Journal of Pharmacological Sciences, 2013
To develop a simple screening system for blockers of voltage-gated Kv1.3 and Kv1.5 channels, new cell lines co-expressing mutated Nav1.5 (IFM/Q3), Kir2.1 (Kir), and Kv1.3 or Kv1.5 were introduced as IFM/Q3+Kir+Kv1.3 and IFM/Q3+Kir+Kv1.5, respectively ...
Masato Fujii, Keisuke Hayashi, Susumu Ohya, Hisao Yamamura, Yuji Imaizumi   +4 more
doaj   +1 more source