Results 181 to 190 of about 577,472 (296)

Pollen donor selection modulates fruit quality, bioactive profiles, and antioxidant capacity in 'Fengtang' plum (Prunus salicina): links to endogenous hormonal regulation. [PDF]

BMC Plant Biol
Deng L, Jin Z, Jin X, Feng Y, Yuan B, Zhang H, Xiong B, Wang X, Sun G, Zhang M, He S, Liao L, Wang Z.   +12 more
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Improving Clinical Outcomes of Encapsulated Faecal Microbiota Transplantation for Clostridioides difficile Infection Through Empirical Donor Selection and Optimised Dosing: A Quality Improvement Study. [PDF]

Aliment Pharmacol Ther
Paaske SE, Baunwall SMD, Rubak T, Rågård N, Kelsen J, Hansen MM, Lødrup AB, Lyhne S, Glavind E, Fernis CMC, Hald S, Erikstrup LT, Vinter-Jensen L, Lal S, Mikkelsen S, Erikstrup C, Dahlerup JF, Hvas CL.   +17 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

New Donor Selection Criteria Result in Optimal Outcomes of Kidneys from Uncontrolled Donation After the Circulatory Determination of Death. [PDF]

Transplant Direct
Campos S, Ballesteros MA, Rodrigo E, López Del Moral C, Campos-Juanatey F, Suberviola B, García-Alcalde L, Amaya A, Domínguez-Gil B, Ruiz-San Millan JC, Miñambres E.   +10 more
europepmc   +1 more source

Donor selection and surgical technique for en bloc liver-small bowel graft procurement [PDF]

, 1993
Abu-Elmagd, K, Casavilla, A, Selby, R, Starzl, TE, Todo, S, Tzakis, A   +5 more
core  

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Convalescent plasma therapy for COVID-19 - Donor selection strategies and establishment of a plasma bank. [PDF]

New Microbes New Infect
Kajova M, Khawaja T, Levonen I, Pietilä JP, Virtanen J, Pakkanen SH, Välimaa H, Nousiainen A, Hepojoki J, Sironen T, Vierikko A, Ihalainen J, Vapalahti O, Kantele A.   +13 more
europepmc   +1 more source

Donor selection for adoptive cell therapy with CD45RA^- memory T cells for patients with coronavirus disease 2019, and dexamethasone and interleukin-15 effects on the phenotype, proliferation and interferon gamma release. [PDF]

Cytotherapy, 2023
Al-Akioui-Sanz K, Pascual-Miguel B, Díaz-Almirón M, Mestre-Durán C, Navarro-Zapata A, Clares-Villa L, Martín-Cortázar C, Vicario JL, Moreno MÁ, Balas A, De Paz R, Minguillón J, Pérez-Martínez A, Ferreras C.   +13 more
europepmc   +1 more source