Results 201 to 210 of about 3,804,425 (381)

Morphological heterogeneity description enabled early and parallel non-invasive prediction of T-cell proliferation inhibitory potency and growth rate for facilitating donor selection of human mesenchymal stem cells [PDF]

, 2022
Yuta Imai, Kei Kanie, Ryuji Kato
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Harnessing HLA Divergence for Improved Donor Selection in Haploidentical Haematopoietic Stem Cell Transplantation. [PDF]

HLA
Jorge Cordeiro D, Villemonteix J, Xhaard A, Ferrary O, Dartois W, Lima BA, Toullec L, Peffault de Latour R, Caillat-Zucman S, Allain V.   +9 more
europepmc   +1 more source

Donor – recipient selection using epitope mismatches in kidney transplantation

, 2021
Andrey Vatazin, A. B. Vatazin, Vadim Stepanov   +2 more
openalex   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

On the channel and type of international disaster aid [PDF]

Research suggests that a donor country’s decision to provide post-disaster assistance is not only driven by the severity of a disaster and the resulting humanitarian needs in the recipient country, but also by strategic considerations.
Raschky, Paul A., Schwindt, Manijeh
core  

Allogeneic Hematopoietic Cell Donor Selection: Contemporary Guidelines from the NMDP/CIBMTR. [PDF]

Transplant Cell Ther
Jimenez Jimenez AM, Spellman SR, Politikos I, McCurdy SR, Devine SM, Malki MMA, Bolon YT, Lee SJ, Dehn J, Pidala J, Maiers M, Askar M, Malmberg C, Auletta JJ, Stefanski H, Broglie L, Qayed M, Horwitz M, Wilder JS, Gooptu M, Mehta RS, Fernandez-Viña M, Shaw BE, Shaffer BC.   +23 more
europepmc   +1 more source

Impact of errors of creatinine and cystatin C equations in the selection of living kidney donors [PDF]

, 2019
Ana González‐Rinne, Sergio Luis‐Lima, Beatriz Escamilla, Natalia Negrín‐Mena, Ana I. Ramı́rez, Adelaida Morales, Nicanor Vega, Patricia García, Elisa Cabello, Domingo Marrero-Miranda, Ana Aldea‐Perona, Alejandra Boto Álvarez, Maria del Carmen Beceiro Abad, Lourdes Pérez Tamajón, Federico González‐Rinne, Alejandra González‐Delgado, Laura Díaz‐Martín, Alejandro Jiménez, Armando Torres, Esteban Porrini   +19 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Microbiota composition-based donor selection affects FMT efficacy in a murine colitis model. [PDF]

Front Immunol
Dai Z, Cheng W, Peng H, Qiu X, Sun J, Liu X, Sun X, Cai J, Wang J, Li G, Lv Y, Chen S, Zhong Z.   +12 more
europepmc   +1 more source