Results 211 to 220 of about 3,804,425 (381)

Donor heart selection: Evidence-based guidelines for providers.

The Journal of Heart and Lung Transplantation, 2022
H. Copeland, I. Kneževič, D. Baran, V. Rao, M. Pham, F. Gustafsson, S. Pinney, B. Lima, M. Masetti, A. Ciarka, N. Rajagopalan, A. Torres, E. Hsich, J. Patel, L. Goldraich, Monica M Colvin, J. Segovia, H. Ross, M. Ginwalla, B. Sharif-Kashani, M. Farr, L. Potena, J. Kobashigawa, M. Crespo-Leiro, N. Altman, Florian Wagner, J. Cook, V. Stosor, P. Grossi, K. Khush, T. Yağdı, S. Restaino, S. Tsui, D. Absi, G. Sokos, A. Zuckermann, Brian Wayda, J. Felius, S. Hall   +38 more
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Donor Selection for Heart Transplantation in 2025. [PDF]

JACC Heart Fail
Jain R, Kransdorf EP, Cowger J, Jeevanandam V, Kobashigawa JA.   +4 more
europepmc   +1 more source

Maintaining an adequate sperm donor pool: modifying the medical criteria for sperm donor selection. [PDF]

J Assist Reprod Genet, 2021
Pennings G.
europepmc   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Pollen donor selection modulates fruit quality, bioactive profiles, and antioxidant capacity in 'Fengtang' plum (Prunus salicina): links to endogenous hormonal regulation. [PDF]

BMC Plant Biol
Deng L, Jin Z, Jin X, Feng Y, Yuan B, Zhang H, Xiong B, Wang X, Sun G, Zhang M, He S, Liao L, Wang Z.   +12 more
europepmc   +1 more source

Advanced seedless donors among grape varieties of the Anapa zonal experimental station for grape growing and wine making (AZESGGAWM) selection

, 2020
Иван Викторович Горбунов, A. A. Lukyanova, A.A. Lukyanov, Yulia Aleksandrovna Akhmedova   +3 more
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Improving Clinical Outcomes of Encapsulated Faecal Microbiota Transplantation for Clostridioides difficile Infection Through Empirical Donor Selection and Optimised Dosing: A Quality Improvement Study. [PDF]

Aliment Pharmacol Ther
Paaske SE, Baunwall SMD, Rubak T, Rågård N, Kelsen J, Hansen MM, Lødrup AB, Lyhne S, Glavind E, Fernis CMC, Hald S, Erikstrup LT, Vinter-Jensen L, Lal S, Mikkelsen S, Erikstrup C, Dahlerup JF, Hvas CL.   +17 more
europepmc   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source