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Current Biology, 2022
Dopamine was first described by George Barger, James Ewens, and Henry Dale in 1910 as an epinephrine-like monoamine compound. Initially believed to be a mere precursor of norepinephrine, it was mostly ignored for the next four decades (Figure 1A). However, in the 1950s Kathleen Montagu showed that dopamine occurred in the brain by itself, and a series ...
Kauê Machado, Costa +1 more
openaire +2 more sources
Dopamine was first described by George Barger, James Ewens, and Henry Dale in 1910 as an epinephrine-like monoamine compound. Initially believed to be a mere precursor of norepinephrine, it was mostly ignored for the next four decades (Figure 1A). However, in the 1950s Kathleen Montagu showed that dopamine occurred in the brain by itself, and a series ...
Kauê Machado, Costa +1 more
openaire +2 more sources
The Lancet, 1976
The antipsychotic actions and extra-pyramidal side-effects of neuroleptic drugs are strongly correlated with their ability to block central dopaminergic transmission. It is argued that the former are more closely related to actions on dopaminergic mechanisms in the "mesolimbic dopamine" system, and the latter to similar actions in the striatum ...
Crow, T J +3 more
+12 more sources
The antipsychotic actions and extra-pyramidal side-effects of neuroleptic drugs are strongly correlated with their ability to block central dopaminergic transmission. It is argued that the former are more closely related to actions on dopaminergic mechanisms in the "mesolimbic dopamine" system, and the latter to similar actions in the striatum ...
Crow, T J +3 more
+12 more sources
Extremfrühgeborene: Begünstigt Dopamin Infektionen?
Neonatologie Scan, 2021Die Wissenschaftlerinnen und Wissenschaftler werteten die Daten von 258 Frühgeborenen aus, welche zwischen 2009 und 2018 im Gestationsalter unter 28 Schwangerschaftswochen zur Welt gekommen waren.
semanticscholar +1 more source
Dopamine and non-dopamine psychoses
Psychopharmacology, 1984The time course of antipsychotic response following the initiation of an antipsychotic drug and functional dopamine receptor sensitivity were explored in a cohort of recently admitted psychotic (mood-incongruent) patients. The distribution of the latencies of antipsychotic response suggested at least two populations.
D L, Garver +4 more
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Psychose: Reduzierte Dopamin-Synthesekapazität in der Remission?
Fortschritte der Neurologie Psychiatrie, 2020Abnormalitäten des Dopaminstoffwechsels gelten heute als wesentliche Ursache für psychotische Erkrankungen. Die Synthesekapazität von Dopamin in Neuronen des Striatums scheint dabei eine besondere Rolle zu spielen. Ob die Produktion des Transmitters auch
semanticscholar +1 more source
Journal of Neural Transmission, 1993
The dopamine hypothesis of schizophrenia and the emphasis on other neurotransmitters, most notably norepinephrine, serotonin, and acetylcholine, in the pathogenesis of depression, have focused attention away from substantial evidence implicating dopamine in affective disorders.
A S, Brown, S, Gershon
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The dopamine hypothesis of schizophrenia and the emphasis on other neurotransmitters, most notably norepinephrine, serotonin, and acetylcholine, in the pathogenesis of depression, have focused attention away from substantial evidence implicating dopamine in affective disorders.
A S, Brown, S, Gershon
openaire +2 more sources

