Results 121 to 130 of about 506,450 (362)

Glutamate and dopamine in schizophrenia: An update for the 21st century

open access: yesJournal of Psychopharmacology, 2015
The glutamate and dopamine hypotheses are leading theories of the pathoaetiology of schizophrenia. Both were initially based on indirect evidence from pharmacological studies supported by post-mortem findings, but have since been substantially advanced ...
O. Howes, R. McCutcheon, J. Stone
semanticscholar   +1 more source

Modification of Metal Microelectrodes with Vertical Graphene Structure for Enhanced Electrochemical Detection of Dopamine

open access: yesAdvanced Materials Interfaces, EarlyView.
In this article, vertical graphene‐modified microelectrodes (VGMEs) are fabricated by modifying vertical graphene on different types of metal microelectrodes (Au, Ti, Ag, and W) for enhanced electrochemical detection of DA. Moreover, the sensing performance on dopamine concentrations is explored with different electrochemical methods, including EIS, CV,
Lukang Gao   +9 more
wiley   +1 more source

Dopamine: A Research Framework for Deep Reinforcement Learning [PDF]

open access: yesarXiv, 2018
Deep reinforcement learning (deep RL) research has grown significantly in recent years. A number of software offerings now exist that provide stable, comprehensive implementations for benchmarking. At the same time, recent deep RL research has become more diverse in its goals.
arxiv  

THE DEPRESSOR ACTION OF DOPAMINE AND ADRENALINE [PDF]

open access: bronze, 1958
J. H. Burn, M. J. Rand
openalex   +1 more source

Dopamine: generalization and bonuses

open access: yesNeural Networks, 2002
In the temporal difference model of primate dopamine neurons, their phasic activity reports a prediction error for future reward. This model is supported by a wealth of experimental data. However, in certain circumstances, the activity of the dopamine cells seems anomalous under the model, as they respond in particular ways to stimuli that are not ...
Kakade, Sham, Dayan, Peter
openaire   +7 more sources

Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules

open access: yesAdvanced Materials Interfaces, EarlyView.
This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania   +2 more
wiley   +1 more source

The role of dopamine in schizophrenia from a neurobiological and evolutionary perspective: old fashioned, but still in vogue.

open access: yesFrontiers in Psychiatry, 2014
: Dopamine is an inhibitory neurotransmitter involved in the pathology of schizophrenia.The revised dopamine hypothesis states that dopamine abnormalities in the mesolimbic and prefrontal brain regions exist in schizophrenia. However, recent research has
Ralf eBrisch   +11 more
doaj   +1 more source

Neuromelanin-sensitive MRI as a noninvasive proxy measure of dopamine function in the human brain

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance Neuromelanin-sensitive MRI (NM-MRI) purports to detect the content of neuromelanin (NM), a product of dopamine metabolism that accumulates in the substantia nigra (SN).
C. Cassidy   +15 more
semanticscholar   +1 more source

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