Results 121 to 130 of about 835,082 (382)

Delighting in dopamine [PDF]

open access: yesNature Methods, 2018
The genetically encoded sensor dLight1 reports dopamine release in culture, slices and behaving mice.
openaire   +2 more sources

Dopamine and Dopamine-Related Ligands Can Bind Not Only to Dopamine Receptors

open access: yesLife, 2022
The dopaminergic system is one of the most important neurotransmitter systems in the central nervous system (CNS). It acts mainly by activation of the D1-like receptor family at the target cell. Additionally, fine-tuning of the signal is achieved via pre-synaptic modulation by the D2-like receptor family.
openaire   +3 more sources

Dopamine neurons create Pavlovian conditioned stimuli with circuit-defined motivational properties

open access: yesNature Neuroscience, 2018
Environmental cues, through Pavlovian learning, become conditioned stimuli that guide animals toward the acquisition of rewards (for example, food) that are necessary for survival. We tested the fundamental role of midbrain dopamine neurons in conferring
Benjamin T. Saunders   +3 more
semanticscholar   +1 more source

3D Printing Strategies for Bioengineering Human Cornea

open access: yesAdvanced Healthcare Materials, EarlyView.
This review highlights recent progress in 3D bioprinting strategies for engineering human corneas. Key aspects include the replication of corneal transparency, curvature, and biomechanical properties, alongside innovations in recent advancements in 3D printing methods, which benefit in overcoming current challenges.
Yunong Yuan   +4 more
wiley   +1 more source

Mesolimbic dopamine ramps reflect environmental timescales

open access: yeseLife
Mesolimbic dopamine activity occasionally exhibits ramping dynamics, reigniting debate on theories of dopamine signaling. This debate is ongoing partly because the experimental conditions under which dopamine ramps emerge remain poorly understood.
Joseph R Floeder   +3 more
doaj   +1 more source

Optogenetic stimulation of VTA dopamine neurons reveals that tonic but not phasic patterns of dopamine transmission reduce ethanol self-administration

open access: yesFrontiers in Behavioral Neuroscience, 2013
There is compelling evidence that acute ethanol exposure stimulates ventral tegmental area (VTA) dopamine cell activity and that VTA-dependent dopamine release in terminal fields within the nucleus accumbens plays an integral role in the regulation of ...
Caroline E Bass   +7 more
doaj   +1 more source

Effects of Atomoxetine on Motor and Cognitive Behaviors and Brain Electrophysiological Activity of Dopamine Transporter Knockout Rats [PDF]

open access: gold, 2022
Maria Ptukha   +7 more
openalex   +1 more source

Injectable Dual‐Crosslinked Poly(oligo(Ethylene Glycol) Methacrylate) Hydrogels Inspired by Mussel Adhesion for Cutaneous Wound Healing and Functional Tissue Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
Injectable POEGMA‐DA hydrogels, dual‐crosslinked via dopamine self‐polymerization and dynamic hydrazone bonds, provide a safer alternative to invasive wound closure methods and toxic bioadhesives. Mimicking skin‐like mechanics, they achieve effective tissue adhesion for acute dermal wounds, supporting improved healing outcomes, including reducing ...
Gurpreet Kaur Randhawa   +6 more
wiley   +1 more source

Dopamine D2 Receptor Signaling Attenuates Acinar Cell Necroptosis in Acute Pancreatitis through the Cathepsin B/TFAM/ROS Pathway [PDF]

open access: hybrid, 2022
Zengkai Wu   +8 more
openalex   +1 more source

Magnetic Bioprinting and Actuation of Stretchable Muscle Tissue

open access: yesAdvanced Healthcare Materials, EarlyView.
Human and murine myoblasts labeled with iron oxide nanoparticles are magnetically bioprinted into wrench‐shaped tissues, which are then anchored between two magnetic needles. Mechanical stretching of these tissues enhances both their maturation and functional performance. Abstract Engineering tissues with precise, long‐lasting shapes and the capability
Noam Demri   +6 more
wiley   +1 more source

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