Results 291 to 300 of about 506,450 (362)

The absence of Pitx3 results in postnatal loss of dopamine neurons and is associated with an increase in the pro-apoptotic Bcl2 factor Noxa and cleaved caspase 3. [PDF]

Cell Death Dis
Kouwenhoven WM, Robinson EJ, Hamberg D, von Oerthel L, Smidt MP, van der Heide LP.   +5 more
europepmc   +1 more source

Adult Neurogenesis in the Subventricular Zone of Patients with Huntington's and Parkinson's Diseases and following Long‐Term Treatment with Deep Brain Stimulation

Annals of Neurology, EarlyView.
Objective Parkinson's and Huntington's diseases are characterized by progressive neuronal loss. Previous studies using human postmortem tissues have shown the impact of neurodegenerative disorders on adult neurogenesis. The extent to which adult neural stem cells are activated in the subventricular zone and whether therapeutic treatments such as deep ...
Marta Snapyan, Francis Desmeules, Jonathan Munro, Morgan Bérard, Stephan Saikali, Peter V. Gould, Maxime Richer, Emmanuelle Pourcher, Mélanie Langlois, Anne‐Marie Dufresne, Michel Prud'homme, Léo Cantin, André Parent, Armen Saghatelyan, Martin Parent   +14 more
wiley   +1 more source

Effects of GLP-1 Receptor Agonists in Alcohol Use Disorder. [PDF]

Basic Clin Pharmacol Toxicol
Klausen MK, Knudsen GM, Vilsbøll T, Fink-Jensen A.   +3 more
europepmc   +1 more source

Spiking Patterns in the Globus Pallidus Highlight Convergent Neural Dynamics across Diverse Genetic Dystonia Syndromes

Annals of Neurology, EarlyView.
Objective Genetic dystonia is a complex movement disorder with diverse clinical manifestations resulting from pathogenic mutations in associated genes. A recent paradigm shift emphasizes the functional convergence among dystonia genes, hinting at a shared pathomechanism. However, the neural dynamics supporting this convergence remain largely unexplored.
Ahmet Kaymak, Fabiana Colucci, Mahboubeh Ahmadipour, Nico Golfrè Andreasi, Sara Rinaldo, Zvi Israel, David Arkadir, Roberta Telese, Vincenzo Levi, Giovanna Zorzi, Jacopo Carpaneto, Miryam Carecchio, Holger Prokisch, Michael Zech, Barbara Garavaglia, Hagai Bergman, Roberto Eleopra, Alberto Mazzoni, Luigi M. Romito   +18 more
wiley   +1 more source

Novel dopaminergic neurotransmission in theOctopusvisual system

Courtney A, Styfhals R, Van Dijck M, Boulanger J, Geenen L, Lanoizelet M, Hardege I, Lassnig M, Jansson AM, Gehler-Rahman J, Almansa E, Obenhaus HA, Seuntjens E, Schafer WR.   +13 more
europepmc   +1 more source

Focused Ultrasound Modulates Dopamine in a Mesolimbic Reward Circuit. [PDF]

J Neurochem
Olaitan G, Ganesana M, Strohman A, Lynch WJ, Legon W, Venton BJ.   +5 more
europepmc   +1 more source

Validating the Accuracy of Parkinson's Disease Clinical Diagnosis: A UK Brain Bank Case–Control Study

Annals of Neurology, EarlyView.
Objective Despite diagnostic criteria refinements, Parkinson's disease (PD) clinical diagnosis still suffers from a not satisfying accuracy, with the post‐mortem examination as the gold standard for diagnosis. Seminal clinicopathological series highlighted that a relevant number of patients alive‐diagnosed with idiopathic PD have an alternative post ...
Lazzaro di Biase, Pasquale Maria Pecoraro, Vincenzo Di Lazzaro   +2 more
wiley   +1 more source

Characterization of the atypical antipsychotic drug aripiprazole cytotoxicity in the neutrophil model cell line HL-60. [PDF]

PLoS One
Swain CA, Robbs EJ, Verma L, Brandt H, Seppaenen AL, Cavnar PJ.   +5 more
europepmc   +1 more source

Psychoses of Epilepsy: Unravelling the Phenotypic and Genotypic Features

Annals of Neurology, EarlyView.
Objectives We analyzed the genotypic and phenotypic features of patients with psychosis of epilepsy (POE). Methods Patients with POE recruited to an epilepsy genetics research program underwent phenotyping and genetic analysis. The latter included screening for rare pathogenic variants in epilepsy genes, and polygenic risk score (PRS) calculation for ...
Genevieve Rayner, Eliza Honybun, Melanie Bahlo, Karen L. Oliver, Ingrid E. Scheffer   +4 more
wiley   +1 more source

<i>WWC1</i> mutation drives dopamine dysregulation and synaptic imbalance in Tourette's syndrome. [PDF]

Sci Adv
Lv J, Liang S, Qin P, Liu X, Ge X, Guo Y, Xia S, Jing W, Lu Y, Zhang T, Li H.   +10 more
europepmc   +1 more source