Results 341 to 350 of about 826,720 (382)
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The Lancet, 1976
The antipsychotic actions and extra-pyramidal side-effects of neuroleptic drugs are strongly correlated with their ability to block central dopaminergic transmission. It is argued that the former are more closely related to actions on dopaminergic mechanisms in the "mesolimbic dopamine" system, and the latter to similar actions in the striatum ...
Jakob Korf, BenH.C. Westerink
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The antipsychotic actions and extra-pyramidal side-effects of neuroleptic drugs are strongly correlated with their ability to block central dopaminergic transmission. It is argued that the former are more closely related to actions on dopaminergic mechanisms in the "mesolimbic dopamine" system, and the latter to similar actions in the striatum ...
Jakob Korf, BenH.C. Westerink
+16 more sources
Dopamine and non-dopamine psychoses
Psychopharmacology, 1984The time course of antipsychotic response following the initiation of an antipsychotic drug and functional dopamine receptor sensitivity were explored in a cohort of recently admitted psychotic (mood-incongruent) patients. The distribution of the latencies of antipsychotic response suggested at least two populations.
David L. Garver +4 more
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Science, 1997
Ingrid Wickelgren's Special News Report “Getting the brain's attention” ([3 Oct., p. 35][1]) presents the views of those who question the current orthodoxy that dopamine acts in the nucleus accumbens as a key neurotransmitter underlying the behavioral effects of positive reinforcement or ...
Jeffrey A. Gray +2 more
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Ingrid Wickelgren's Special News Report “Getting the brain's attention” ([3 Oct., p. 35][1]) presents the views of those who question the current orthodoxy that dopamine acts in the nucleus accumbens as a key neurotransmitter underlying the behavioral effects of positive reinforcement or ...
Jeffrey A. Gray +2 more
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Journal of Neural Transmission, 1993
The dopamine hypothesis of schizophrenia and the emphasis on other neurotransmitters, most notably norepinephrine, serotonin, and acetylcholine, in the pathogenesis of depression, have focused attention away from substantial evidence implicating dopamine in affective disorders.
Samuel Gershon, A. S. Brown
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The dopamine hypothesis of schizophrenia and the emphasis on other neurotransmitters, most notably norepinephrine, serotonin, and acetylcholine, in the pathogenesis of depression, have focused attention away from substantial evidence implicating dopamine in affective disorders.
Samuel Gershon, A. S. Brown
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Dopamine turnover estimated by simultaneous LCEC assay of dopamine and dopamine metabolites
Journal of Pharmacological Methods, 1982The estimation of changes in tissue levels of dopamine (DA) and its metabolites has been employed to approximate the turnover rate or release of DA. We have developed an assay using high pressure liquid chromatography with electrochemical detection to quantify DA, dihydroxyphenylacetic acid (DOPAC), 3-methoxytyramine (3-MT), and homovanillic acid (HVA)
C.H. Cheng, G.F. Wooten
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Neurology, 1997
This review summarizes a growing body of biological, pharmacologic, and genetic data that support a role for dopamine in the pathophysiology of certain subtypes of migraine. Most migraine symptoms can be induced by dopaminergic stimulation. Moreover, there is dopamine receptor hypersensitivity in migraineurs, as demonstrated by the induction of yawning,
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This review summarizes a growing body of biological, pharmacologic, and genetic data that support a role for dopamine in the pathophysiology of certain subtypes of migraine. Most migraine symptoms can be induced by dopaminergic stimulation. Moreover, there is dopamine receptor hypersensitivity in migraineurs, as demonstrated by the induction of yawning,
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Dopamine receptors and the dopamine hypothesis of schizophrenia
Synapse, 1987AbstractThe discovery of neuroleptic drugs in 1952 provided a new strategy for seeking a biological basis of schizophrenia. This entailed a search for a primary site of neuroleptic action. The Parkinsonian effects caused by neuroleptics suggested that dopamine transmission may be disrupted by these drugs.
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Brain Research, 2006 Social attachments play a central role in human society. In fact, such attachments are so important that deficits in the ability to form meaningful social bonds are associated with a variety of psychological disorders. Although mother-infant bonding has been studied for many years, we only recently have begun to examine the processes that underlie ...
J. Thomas Curtis +3 more
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Clinical Science, 1982
It would seem established beyond peradventure that dopamine is formed in the kidney from circulating L-dopa. The likely site would appear to be the renal tubular cells but the contribution of the renal dopaminergic nerves needs further evaluation. Moreover it is probably that dopamine formed within the kidney acts there on specific receptors.
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It would seem established beyond peradventure that dopamine is formed in the kidney from circulating L-dopa. The likely site would appear to be the renal tubular cells but the contribution of the renal dopaminergic nerves needs further evaluation. Moreover it is probably that dopamine formed within the kidney acts there on specific receptors.
openaire +2 more sources