Results 61 to 70 of about 88,842 (261)

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

Genetic and pharmacological evidence that endogenous nociceptin/orphanin FQ contributes to dopamine cell loss in Parkinson's disease

Neurobiology of Disease, 2016
To investigate whether the endogenous neuropeptide nociceptin/orphanin FQ (N/OFQ) contributes to the death of dopamine neurons in Parkinson's disease, we undertook a genetic and a pharmacological approach using NOP receptor knockout (NOP−/−) mice, and ...
Ludovico Arcuri, Riccardo Viaro, Simone Bido, Francesco Longo, Mariangela Calcagno, Pierre-Olivier Fernagut, Nurulain T. Zaveri, Girolamo Calò, Erwan Bezard, Michele Morari   +9 more
doaj   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

Preventing Broodiness in Turkey Hens with a Dopamine Receptor Blocking Agent

Poultry Science, 1980
Pimozide, a dopamine receptor blocking agent, was administered to turkey hens which were judged, on the basis of an increased nesting frequency, to be in transition between the laying and broody phases of a reproductive cycle. Treatment of hens with pimozide, either by subcutaneous injection or oral administration significantly decreased daily nest ...
J R, Millam, W H, Burke, M E, El Halawani, L A, Ogren   +3 more
openaire   +2 more sources

The Effects of Red Grape Juice and Exercise on Parkinson's Disease in Male Rats

مجله دانشکده پزشکی اصفهان, 2012
Background: Neural degeneration is induced by production of oxidant agents in neural pools. Red grape juice has antioxidant agents. Exercise can be able to protect dopaminergic neurons of brain.
Fatemeh Eshraghi Jazi, Hojjatollah Alaei, Hamid Azizi Malekabadi, Ali Asghar Pilehvarian, Mahin Gharavi Naeini, Mohammad Saleh Ahmadi, Emad Shah-Mansouri, Zahra Ciahmard   +7 more
doaj  

A Bio-Inspired Dopamine Model for Robots with Autonomous Decision-Making

Biomimetics
Decision-making systems allow artificial agents to adapt their behaviours, depending on the information they perceive from the environment and internal processes.
Marcos Maroto-Gómez, Javier Burguete-Alventosa, Sofía Álvarez-Arias, María Malfaz, Miguel Ángel Salichs   +4 more
doaj   +1 more source

Altered dopamine ontogeny in the developmentally vitamin D deficient rat and its relevance to schizophrenia

Frontiers in Cellular Neuroscience, 2013
Schizophrenia is a heterogeneous group of disorders with unknown aetiology. Although abnormalities in multiple neurotransmitter systems have been linked to schizophrenia, alterations in dopamine neurotransmission remain central to the treatment of this ...
James P. Kesby, Xiaoying eCui, Thomas H.J. Burne, Thomas H.J. Burne, Darryl Wakter Eyles, Darryl Wakter Eyles   +5 more
doaj   +1 more source

Development of a Human 3D Immune‐Competent Neurovascular Model Enabling Time‐Resolved Monitoring of Neuroinflammatory Dynamics and Neuroimmune Interactions

Advanced Science, EarlyView.
Neuroinflammation alters blood–brain barrier integrity and contributes to neurological disorders, yet existing models lack human immune complexity. This study presents a 3D, immune‐responsive platform that reconstructs key neurovascular components and enables real‐time monitoring.
Pavlo Gordiichuk, Jing Bai, Olurotimi A. Bolonduro, Andrew M. Silverman, Robert Madison Green, Jason H. Lasser, Paul W. Fleming, Lishomwa C. Ndhlovu, James F. Saunders, Dmitry Shvartsman   +9 more
wiley   +1 more source

Comparison of Effects of Light Anesthetics, Diethyl Ether and Carbon Dioxide, on Hypothalamic Paraventricular Nucleus D1 and D2 Dopamine Receptors- and Glucosensitive Neurons-Induced Food Intake in Fasted Conscious Rats

Basic and Clinical Neuroscience, 2018
Introduction: Carbon Dioxide (CO2) and diethyl ether are used as light anesthetics. However, experimental data about their side effects are scarce.
Masoud Shareghi Brojeni, Morteza Salimi, Zahra Mirmohammadsadeghi, Abbas Haghparast, Afsaneh Eliassi   +4 more
doaj  

Comparison of Sympathomimetics in the Correction of Arterial Hypotension during Combined Anesthesia

Общая реаниматология, 2012
Objective: to make a comparative assessment of hemodynamic parameters when correcting combined anesthesia-induced arterial hypotension with dopamine, adrenaline, mesatone, or noradrenaline. Subjects and methods.
D. B. Borisov, O. V Krylov, A. A. Kapinos, S. V Yudin, N. A. Istomina   +4 more
doaj   +1 more source