Results 71 to 80 of about 3,949,650 (302)

Near‐Infrared‐Driven Metal–Organic Frameworks‐Based Nanorobots for Controlled Photothermal‐Chemical Therapy Synergistic Induction of Cancer Cell Death

Advanced Robotics Research, EarlyView.
To achieve efficient cancer cell death, a bowl‐shaped PDA@UiO‐66@DOX nanorobot drug‐delivery nanoplatform was developed. Near‐infrared irradiation not only drives the nanorobot to exhibit self‐thermophoretic motion and elevates temperature but also triggers Doxorubicin (DOX) release via hyperthermia, enhancing cancer cells uptake of DOX and thereby ...
Tong Lin, Jie Yang, Yongcheng Li, Yuepeng Cai, Xiaosong Zhou, Ting Chen, Renfeng Dong   +6 more
wiley   +1 more source

The Effects of Red Grape Juice and Exercise on Parkinson's Disease in Male Rats

مجله دانشکده پزشکی اصفهان, 2012
Background: Neural degeneration is induced by production of oxidant agents in neural pools. Red grape juice has antioxidant agents. Exercise can be able to protect dopaminergic neurons of brain.
Fatemeh Eshraghi Jazi, Hojjatollah Alaei, Hamid Azizi Malekabadi, Ali Asghar Pilehvarian, Mahin Gharavi Naeini, Mohammad Saleh Ahmadi, Emad Shah-Mansouri, Zahra Ciahmard   +7 more
doaj  

A Bio-Inspired Dopamine Model for Robots with Autonomous Decision-Making

Biomimetics
Decision-making systems allow artificial agents to adapt their behaviours, depending on the information they perceive from the environment and internal processes.
Marcos Maroto-Gómez, Javier Burguete-Alventosa, Sofía Álvarez-Arias, María Malfaz, Miguel Ángel Salichs   +4 more
doaj   +1 more source

Comparison of Sympathomimetics in the Correction of Arterial Hypotension during Combined Anesthesia

Общая реаниматология, 2012
Objective: to make a comparative assessment of hemodynamic parameters when correcting combined anesthesia-induced arterial hypotension with dopamine, adrenaline, mesatone, or noradrenaline. Subjects and methods.
D. B. Borisov, O. V Krylov, A. A. Kapinos, S. V Yudin, N. A. Istomina   +4 more
doaj   +1 more source

DRD2 Deficiency Underlies Pituitary Adenoma Dependent on Escherichia coli Translocation from the Gut

Advanced Science, EarlyView.
Dopamine receptor D2 (DRD2) deficiency disrupts epithelial barrier integrity in both the gut and pituitary gland, facilitating translocation of gut‐derived Escherichia coli into pituitary tissue. Intratumoral E. coli are phagocytosed by microglia, triggering GSDMD‐dependent pyroptosis and HMGB1 release, which subsequently activates MAPK signaling to ...
Xian‐jun Su, Li Ma, Xi Xiong, Jun‐hua Meng, Qi Wu, Yu Zhang, Shu‐guang Dong, Yue‐fei Wang, Jin‐hu Wu, Qing‐yuan Zeng, Hong‐feng Zhang, Li‐li Li, Liang Meng, Min Peng, Xiao‐dong Huang, Li‐quan Wu, Xiong Wang   +16 more
wiley   +1 more source

Comparison of Effects of Light Anesthetics, Diethyl Ether and Carbon Dioxide, on Hypothalamic Paraventricular Nucleus D1 and D2 Dopamine Receptors- and Glucosensitive Neurons-Induced Food Intake in Fasted Conscious Rats

Basic and Clinical Neuroscience, 2018
Introduction: Carbon Dioxide (CO2) and diethyl ether are used as light anesthetics. However, experimental data about their side effects are scarce.
Masoud Shareghi Brojeni, Morteza Salimi, Zahra Mirmohammadsadeghi, Abbas Haghparast, Afsaneh Eliassi   +4 more
doaj  

Midbrain PAG Astrocytes Modulate Mouse Defensive and Panic‐Like Behaviors

Advanced Science, EarlyView.
Astrocytes in the midbrain periaqueductal gray (PAG) dynamically encode threat intensity and shape defensive action selection in mice. Real‐time Ca2+ imaging reveals robust astrocytic activation during predator odor and CO2 exposure. Aberrant astrocytic Ca2+ overactivation disrupts goal‐directed escape, biases behavior toward freezing, and induces ...
Ellane Barcelon, Kyungchul Noh, Minkyu Hwang, Yoon‐Jung Kim, Unjin Lee, Yeon Joo Ryu, Je‐Kyung Ryu, Sang Beom Jun, Se‐Young Choi, Woo‐Hyun Cho, Sung Joong Lee   +10 more
wiley   +1 more source

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

Advanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang, Zibin Li, Yao Xiao, Ji Bian, Caian He, Chao Liu, Lan Gong, Lin Han, Zhigang Liu, Min Wang   +9 more
wiley   +1 more source

Preparation and properties of silver-carrying nano-titanium dioxide antimicrobial agents and silicone composite

Scientific Reports
The characteristics of dopamine self-polymerization were used to cover the nano-titanium dioxide (TiO2) surface and produce nano-titanium dioxide-polydopamine (TiO2-PDA).
Dongdong Hao, Yuxuan Zhang, Yonghong Ding, Qiuyu Yan   +3 more
doaj   +1 more source

The Promise of Neuroprotective Agents in Parkinson’s Disease

Frontiers in Neurology, 2011
Parkinson’s Disease is characterized by loss of dopamine neurons in the substantia nigra of the brain. Since there are limited treatment options for PD, neuroprotective agents are currently being tested as a means to slow disease progression.
Judith ePotashkin, Stacey E Seidl
doaj   +1 more source