Results 101 to 110 of about 554,589 (315)
Dopamine agonist withdrawal syndrome and non-motor symptoms after Parkinson's disease surgery.
Brain : a journal of neurology, 2010 ARTICLE Sir, I read with interest the manuscript by Dr Thobois and colleagues (Thobois et al. , 2010), in which the authors report the occurrence of depression and apathy after deep brain stimulation surgery for Parkinson’s disease and correlate these ...
M. Nirenberg
semanticscholar +1 more source
International Journal of Eating Disorders, EarlyView.ABSTRACT Objective Avoidant restrictive food intake disorder (ARFID) is a relatively new diagnostic entity, and no medication has been approved. Recent data suggest that mirtazapine, a tetracyclic antidepressant, could improve outcomes in ARFID. We conducted a retrospective chart review to examine the effects of mirtazapine on ARFID treatment in youth.
Aman Chishti +6 more
wiley +1 more source
A computational model revealing the effect of dopamine on action selection [PDF]
arXiv, 2015 In order to reveal the effect of nigrostriatal dopamine system on action selection, first a computational model of the cortex-basal ganglia-thalamus loop is proposed and based on this model a simple compound model realizing the Stroop effect is established.
arxiv
Design Paradigms Based on Spring Agonists for Underactuated Robot Hands: Concepts and Application [PDF]
arXiv, 2020 In this paper, we focus on a rarely used paradigm in the design of underactuated robot hands: the use of springs as agonists and tendons as antagonists. We formalize this approach in a design matrix also considering its interplay with the underactuation method used (one tendon for multiple joints vs. multiple tendons on one motor shaft).
arxiv
Exploring biomarkers of neurodegeneration in epilepsy: Critical insights
Epileptic Disorders, EarlyView.Abstract The advent of biofluid biomarkers for neurodegenerative disorders has precipitated a surge in recent evidence regarding their role in epilepsy. In this literature review, we examine the diagnostic, prognostic, and therapeutic potential of several biomarkers, including amyloid‐beta (Aβ) protein, total (t‐tau), phosphorylated tau (p‐tau) protein,
Rida Farhan +7 more
wiley +1 more source
Exploration, EarlyView.The discovery of the glymphatic system has opened up a pathway for drug delivery to the brain by circumventing the blood‐brain barrier, which can effectively improve drug utilization. The methods of drug delivery through the glymphatic system include intrathecal injection, intranasal injection, and delivery through the meningeal lymphatic vessels.
Xiang Wang +7 more
wiley +1 more source
Molecular dynamics simulations reveal the role of ceramicine B as novel PPARγ partial agonist against type 2 diabetes [PDF]
arXiv, 2018 Peroxisome proliferator-activated receptors gamma (PPAR{\gamma}) are ligand-activated controllers of various metabolic actions and insulin sensitivity. PPAR{\gamma} is thus considered as an important target to treat type 2 diabetes. Available PPAR{\gamma} drugs (full agonists) have robust insulin-sensitizing properties but are accompanied by severe ...
arxiv
Synthetic Biology‐Based Engineering Cells for Drug Delivery
Exploration, EarlyView.Synthetic biology‐based therapeutic cells for drug delivery: Engineered cells effectively transport and release drugs through their intelligence and controllability, such as feedback pathways and external stimuli (e.g., light and ultrasound). The integration of nanotechnology, including nanoparticles, biofilms, and artificial cells, enhances ...
Wenzhe Yi +4 more
wiley +1 more source
Effects of Dopamine Administration on Anxiety in Male Rat
مجله دانشکده پزشکی اصفهان, 2007 Background: Abstract Anxiety is a common disease in the society. Several neurotransmitters. The aim of this study was to investigate indirect effect of dopamine on anxiety in rat.
Hojatallah Alaei +4 more
doaj
Research progress on the mechanisms of pain empathy
Ibrain, EarlyView.This article is related to the graphical research progress of pain empathy, starting with the description of the pain matrix and mirror neurons. Based on the pain matrix and mirror neurons, pain empathy results from the combined action of brain regions such as the anterior cingulate cortex, insula, prefrontal cortex, and amygdala and regulatory ...
Shuangshuang Liu +5 more
wiley +1 more source