Results 101 to 110 of about 333,288 (246)

Data‐Driven Insights into Hyperkinetic Disorders in Neurodevelopmental Syndromes and Epileptic Encephalopathies

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Childhood‐onset hyperkinetic movement disorders occur in a range of genetic conditions. Recently, there has been an increase in recognition of hyperkinetic movement disorders, mainly dystonia, chorea and dyskinesia, with monogenic conditions associated with neurodevelopmental delay (NDD) and also with developmental and epileptic ...
Hugo Morales‐Briceño, Shekeeb S. Mohammad, Rajeshwar Reddy Angiti, Velda Han, Michel Tchan, Russell C. Dale, Victor S.C. Fung   +6 more
wiley   +1 more source

Apathy in Parkinson's Disease: Distinguishing Overlapping Symptoms Via Network Analysis

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Anxiety, fatigue, and excessive daytime sleepiness (EDS) frequently co‐occur in Parkinson's disease (PD) and can influence the clinical determination of apathy. Objective To distinguish patient‐reported apathy from other non‐motor symptoms.
Joseph Seemiller, Abhimanyu Mahajan, Christopher B. Morrow, Joseph F. McGuire, Dawn Bowers, Kelly A. Mills, Gregory M. Pontone   +6 more
wiley   +1 more source

Brexpiprazole mitigates hyperprolactinaemia induced by paliperidone in a patient with a history of skin reaction to aripiprazole: case report introducing a new therapeutic approach

BJPsych Open
Hyperprolactinaemia is a common adverse effect of antipsychotic medication, primarily resulting from dopamine D2 receptor blockade. It is characterised by menstrual irregularities, gynaecomastia, galactorrhoea and, with prolonged exposure, an increased ...
Marie Humbert-Claude, Tiphaine Barbé, Maria-Cristina Ionescu, Mehrnoush Khasian, Omar Timothy Khachouf, Anne-Laure Blanc, Delphine Lemoullec-Tourtier, Nicolas Widmer   +7 more
doaj   +1 more source

Orthostatic Myoclonus—Clinical and Electrophysiological Features in a Large Retrospective Cohort

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Orthostatic myoclonus is characterized by irregular, lower limb myoclonic bursts during stance and is a major cause of postural instability and falls. However, studies are limited, and little is known about its pathophysiology. Objectives We sought to define the clinical and electrophysiological features of orthostatic myoclonus in ...
Sai A. Nagaratnam, Niroshan Jeyakumar, Gobishan Jeyakumar, Florence Chang, Duncan Wilson, Paloma Becker, Hugo Morales‐Briceno, Neil Mahant, Victor S.C. Fung   +8 more
wiley   +1 more source

Therapeutic challenges of giant invasive cystic macroprolactinoma

Endocrinology, Diabetes & Metabolism Case Reports
Giant cystic prolactinomas are extremely rare, with only four cases previously reported in the literature. Herein, we report the case of a 59-year-old male who presented with an acute decline in visual acuity.
S Mekni, H Khiari, S Bouali, R Laamouri, S Essayeh, I Rojbi, I Ben Nacef   +6 more
doaj   +1 more source

Continuous Intrajejunal Levodopa–Carbidopa Infusion in Parkinson's Disease Associated with 22q11.2 Deletion Syndrome: A Case Series

Movement Disorders Clinical Practice, EarlyView.
Abstract Background 22q11.2 deletion syndrome (22q11DS) is a multisystem genetic disorder associated with a significantly increased risk of early‐onset Parkinson's disease (EOPD). Management is challenging because psychiatric and cognitive comorbidities often limit advanced therapies such as deep brain stimulation (DBS). Cases We report 2 patients with
Valle Victor Andrés, Jardel Amory, Hopes Lucie, Clément Guillemette, Lambert Laetitia, Becker Aurélie, Dexheimer Mylène, Bonnet Céline, Frismand Solène, Renaud Mathilde, Puisieux Salomé   +10 more
wiley   +1 more source

NEW DOPAMINE AGONISTS IN CARDIOVASCULAR THERAPY

, 1992
Dopamine, a naturally occurring catecholamine, has been extensively used in intensive care for many years. Dopamine stimulates different types of adrenergic receptors: alpha-1 and -2, beta-1 and -2, and dopamine-1 and -2.
SMIT, AJ, GIRBES, ARJ, VANVELDHUISEN, DJ
core   +1 more source

Longitudinal Associations between Depression, Daytime Sleepiness, and Caregiver Strain in Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Objective Examine the longitudinal relationship between caregiver strain and Parkinson's patient depression, daytime sleepiness, and treatment with dopamine agonists and antidepressants. Background Parkinson's disease (PD) is a neurodegenerative disorder, in which family caregivers play an integral role in patient care.
Sarah Holden, Sean P. Lane, Madison Christopher, Lisa Mann, Julie H. Carter, Joseph Quinn, Jiayun Xu   +6 more
wiley   +1 more source

Dopamine receptors in GtoPdb v.2025.3 [PDF]

Dopamine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Dopamine Receptors [375]) are commonly divided into D1-like (D1 and D5) and D2-like (D2, D3 and D4) families, where the endogenous agonist is ...
Sibley, David R., Sedvall, Goran, Missale, Maria Cristina, Spano, Pierre F., Gainetdinov, Raul R., Civelli, Olivier, Seeman, Philip, Langer, Saloman Z., Carlsson, Arvid, Scatton, Bernard, Kebabian, John W., Beaulieu, Jean-Martin, Borrelli, Emiliana, Espinoza, Stefano, Grandy, David K., Sokoloff, Pierre, Van Tol, Hubert H. M., Schwartz, Jean-Charles, Fisone, Gilberto, Caron, Marc G., Neve, Kim A., Sokoloff, P, Seeman, P, Scatton, B, Sedvall, G, Beaulieu, J-M, Neve, KA, Missale, MC, Schwartz, J-C, Sibley, DR, Spano, PF   +30 more
core   +1 more source

Exercise and Motor Complications in Parkinson's Disease: A Systematic Review and Meta‐Analysis

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Levodopa remains the most effective pharmacological treatment for Parkinson's disease (PD), but long‐term use commonly leads to motor complications such as levodopa‐induced dyskinesia (LID) and motor fluctuations, significantly contributing to disability. Exercise is well‐established for improving motor and non‐motor symptoms in PD;
Priscila Nóbrega‐Sousa, Lucas H.C.C. Santos, Jane Alty, Peter Humburg, Kim Delbaere, Paulo H.S. Pelicioni   +5 more
wiley   +1 more source