Results 1 to 10 of about 28,929 (194)

Reversibility of Cardiac Involvement in Acromegaly Patients After Surgery: 12-Month Follow-up Using Cardiovascular Magnetic Resonance

open access: yesFrontiers in Endocrinology, 2020
PurposeCardiac comorbidity is one of the leading causes of death among acromegaly patients. We aimed to investigate the reversibility of acromegalic cardiac involvement after surgical treatment using the gold standard method, cardiovascular magnetic ...
Xiaopeng Guo   +24 more
doaj   +1 more source

The Epigenomics of Pituitary Adenoma [PDF]

open access: yesFrontiers in Endocrinology, 2019
Background: The vast majority of pituitary tumors are benign and behave accordingly; however, a fraction are invasive and are more aggressive, with a very small fraction being frankly malignant. The cellular pathways that drive transformation in pituitary neoplasms are poorly characterized, and current classification methods are not reliable correlates
Blake M. Hauser   +4 more
openaire   +3 more sources

Patient Characteristics, Diagnostic Delays, Treatment Patterns, Treatment Outcomes, Comorbidities, and Treatment Costs of Acromegaly in China: A Nationwide Study

open access: yesFrontiers in Endocrinology, 2020
PurposeAcromegaly is a rare, intractable endocrine disease. We aimed to describe the patient characteristics, diagnostic delays, treatment patterns, treatment outcomes, comorbidities and treatment costs of acromegaly in China.MethodsThis is a nationwide ...
Xiaopeng Guo   +26 more
doaj   +1 more source

3D Facial Analysis in Acromegaly: Gender-Specific Features and Clinical Correlations

open access: yesFrontiers in Endocrinology, 2018
Objective: Quantitative investigations of facial changes in acromegaly are rare. A new imaging technique, three-dimensional (3D) stereophotography, can accurately quantify whole facial changes.
Xiaopeng Guo   +21 more
doaj   +1 more source

Pituitary adenoma surgery survey: neurosurgical centers and pituitary adenomas

open access: yesBrain and Spine, 2022
Objective. Pituitary adenoma surgery has evolved rapidly in recent decades. This study aims to determine current practice across a wide range of European neurosurgical centers. Methods. A list of eligible departments performing pituitary adenoma surgery was created. The survey consisted of 58 questions.
David Netuka   +9 more
openaire   +6 more sources

Identification and gene expression profiling of human gonadotrophic pituitary adenoma stem cells

open access: yesActa Neuropathologica Communications, 2023
Background Gonadotrophic pituitary adenoma is a major subtype of pituitary adenoma in the sellar region, but it is rarely involved in the hypersecretion of hormones into blood; thus, it is commonly regarded as “non-functioning.” Its tumorigenic ...
Linhao Yuan   +8 more
doaj   +1 more source

Case report: Clinical report of co-occurrence of pituitary adenoma and meningioma in the sellar region after meningioma treatment

open access: yesFrontiers in Neurology, 2022
The coexistence of meningioma and pituitary adenoma is very rare, especially in the same location after meningioma surgery. Here, we reported a case of coexisting meningioma and pituitary adenoma secondary to postoperative meningioma in the sellar region
Wang Lu   +7 more
doaj   +1 more source

Patient-Identified Problems and Influences Associated With Diagnostic Delay of Acromegaly: A Nationwide Cross-Sectional Study

open access: yesFrontiers in Endocrinology, 2021
BackgroundInsidious-onset acromegaly may easily be overlooked by non-specialists of acromegaly and cause diagnostic delay. This study aims to examine the association between diagnostic delay and advice from doctors before any confirmed diagnosis and ...
Kailu Wang   +26 more
doaj   +1 more source

Spectrum of Pituitary disorders: A retrospective study from Basrah, Iraq [version 2; referees: 2 approved]

open access: yesF1000Research, 2018
Background: Pituitary disorders spectrum includes a wide variety of diseases.This study aimed at a comprehensive description of such disorders for patients from  Faiha Specialized Diabetes, Endocrine and Metabolism Center (FDEMC) in Basrah (Southern Iraq)
Abbas Ali Mansour   +11 more
doaj   +1 more source

MDM2 promotes the proliferation and inhibits the apoptosis of pituitary adenoma cells by directly interacting with p53

open access: yesEndokrynologia Polska, 2020
INTRODUCTION: Pituitary adenomas constitute one of the most common intracranial tumours. The mouse double minute 2 homologue (MDM2) is considered as an important oncogene in many tumours, but it has been little studied in pituitary adenomas and the ...
Yibiao Wang   +5 more
doaj   +1 more source

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