Results 161 to 170 of about 554,589 (315)

Cholinergic System Changes in Dopa‐Unresponsive Freezing of Gait in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Freezing of gait (FoG) is a debilitating mobility disturbance that becomes increasingly resistant to dopaminergic pharmacotherapies with advancing Parkinson's disease (PD). The pathophysiology underlying the response of FoG to dopaminergic treatment is poorly understood.
Kelvin L. Chou, Prabesh Kanel, Miriam van Emde Boas, Stiven Roytman, Giulia Carli, Roger L. Albin, Nicolaas I. Bohnen   +6 more
wiley   +1 more source

Phosphodiesterase 10A (PDE10A): Regulator of Dopamine Agonist-Induced Gene Expression in the Striatum. [PDF]

Cells, 2022
Bonate R, Kurek G, Hrabak M, Patterson S, Padovan-Neto F, West AR, Steiner H.   +6 more
europepmc   +1 more source

Biotransformation of l‐DOPA to Dopamine in the Substantia Nigra of Freely Moving Rats: Effect of Dopamine Receptor Agonists and Antagonists [PDF]

, 1998
Sophie Sarre, Diederik Vandeneede, Guy Ebinger, Yvette Michotte   +3 more
openalex   +1 more source

Levodopa‐Carbidopa Intestinal Gel in an Outpatient Setting: A 10‐Year Experience

Movement Disorders Clinical Practice, EarlyView.
Alessandro Magliozzi, Nicholas Feugas, Yu Yan Poon, Taline Naranian, Louis Liu, Yvonne Tse, Anthony E. Lang, Alfonso Fasano   +7 more
wiley   +1 more source

Cortical Effects of Dopamine Replacement Account for Clinical Response Variability in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Individual variability in clinical response to dopamine replacement therapy (DRT) is a key barrier to efficacious treatment for patients with Parkinson's disease (PD). A better understanding of the neurobiological sources of such interindividual differences is necessary to personalize DRT prescribing, inform future clinical ...
Alex I. Wiesman, Mikkel C. Vinding, Panagiota Tsitsi, Per Svenningsson, Josefine Waldthaler, Daniel Lundqvist   +5 more
wiley   +1 more source

Altered Pain Processing Associated with Administration of Dopamine Agonist and Antagonist in Healthy Volunteers. [PDF]

Brain Sci, 2022
Martin SL, Jones AKP, Brown CA, Kobylecki C, Whitaker GA, El-Deredy W, Silverdale MA.   +6 more
europepmc   +1 more source

Pharmacology of reproduction (report 25): Effect of bromocriptine (CB-154), a dopamine agonist on the stimulatory effect of gonadotropin on testicular testosterone levels by the rat

, 1981
Masanao Hirai, Yoshiko Masubuchi, Akiyo Uematsu, Toshio Kumai, K Komoriyama   +4 more
openalex   +1 more source

Dopamine agonists both stimulate and inhibit prolactin release in GH4ZR7 cells [PDF]

, 1999
Annisa Chang, Shin Sh
openalex   +1 more source

Light‐Activated Pharmacological Tools for Exploring the Cholinergic System

Medicinal Research Reviews, EarlyView.
ABSTRACT Cholinergic transmission plays a critical role in both the central and peripheral nervous systems, affecting processes such as learning, memory, and inflammation. Conventional cholinergic drugs generally suffer from poor selectivity and temporal precision, leading to undesired effects and limited therapeutic efficacy. Photopharmacology aims to
Alessio Colleoni, Giulia Galli, Clelia Dallanoce, Marco De Amici, Pau Gorostiza, Carlo Matera   +5 more
wiley   +1 more source

¹¹C-methionine PET aids localization of microprolactinomas in patients with intolerance or resistance to dopamine agonist therapy. [PDF]

Pituitary, 2022
Bashari WA, van der Meulen M, MacFarlane J, Gillett D, Senanayake R, Serban L, Powlson AS, Brooke AM, Scoffings DJ, Jones J, O'Donovan DG, Tysome J, Santarius T, Donnelly N, Boros I, Aigbirhio F, Jefferies S, Cheow HK, Mendichovszky IA, Kolias AG, Mannion R, Koulouri O, Gurnell M.   +22 more
europepmc   +1 more source