Results 171 to 180 of about 554,589 (315)

Effects on turning of microinjections into basal ganglia of D1 and D2 dopamine receptors agonists and the cannabinoid CB1 antagonist SR141716A in a rat Parkinson's model

Neurobiology of Disease, 2004
Brain cannabinoid CB1 receptors are expressed in neural areas that contribute to movement such as basal ganglia, where they co-localize with dopamine D1 and D2 receptors.
Fadwa El Banoua, Isabel Caraballo, Juan A Flores, Beatriz Galan-Rodriguez, Emilio Fernandez-Espejo   +4 more
doaj  

Effects of dopaminergic agonists on rotational behavior and striatal dopamine metabolism following unilateral electrical stimulation of the substantia nigra in the rat

, 1983
Sunao Hata, Hiroshi Watanabe, Kazuo Watanabe   +2 more
openalex   +1 more source

Erratum to Current status of dopamine agonists in Parkinson’s disease [PDF]

, 1996
J L Montastruc, Olivier Rascol, Jean‐Michel Sénard   +2 more
openalex   +1 more source

Recent Developments in the Optical Control of Adrenergic Signaling

Medicinal Research Reviews, EarlyView.
ABSTRACT Adrenoceptors (ARs) play a vital role in various physiological processes and are key therapeutic targets. The advent of optical control techniques, including optogenetics and photopharmacology, offers the potential to modulate AR signaling with precise temporal and spatial resolution. In this review, we summarize the latest advancements in the
Shuang Shi, Yangzhi Cao, Maikel Wijtmans, Henry F. Vischer, Rob Leurs   +4 more
wiley   +1 more source

How resistant are levodopa‐resistant axial symptoms? Response of freezing, posture, and voice to increasing levodopa intestinal infusion rates in Parkinson disease

European Journal of Neurology, Volume 30, Issue 1, Page 96-106, January 2023., 2023
Abstract Background and purpose Treatment of freezing of gait (FoG) and other Parkinson disease (PD) axial symptoms is challenging. Systematic assessments of axial symptoms at progressively increasing levodopa doses are lacking. We sought to analyze the resistance to high levodopa doses of FoG, posture, speech, and altered gait features presenting in ...
Gabriele Imbalzano, Domiziana Rinaldi, Giovanna Calandra‐Buonaura, Manuela Contin, Federica Amato, Giulia Giannini, Luisa Sambati, Claudia Ledda, Alberto Romagnolo, Gabriella Olmo, Pietro Cortelli, Maurizio Zibetti, Leonardo Lopiano, Carlo Alberto Artusi   +13 more
wiley   +1 more source

Locomotor hyperactivity and alterations in dopamine neurotransmission are associated with overexpression of A53T mutant human α-synuclein in mice

Neurobiology of Disease, 2006
Genetic and biochemical abnormalities associated with α-synuclein are implicated in the etiology of Parkinson's disease (PD). In this study, altered locomotor behavior linked to the expression of mutant or wildtype human α-synuclein was investigated ...
Erica L. Unger, David J. Eve, Xiomara A. Perez, Dawn K. Reichenbach, Yanqun Xu, Michael K. Lee, Anne M. Andrews   +6 more
doaj  

Behavioral studies of the effects of dopamine and 5-HT1A agonists in cynomolgus monkeys

, 1989
Eiji Mizuta, Motonori Yamaguchi, Sadako Kuno   +2 more
openalex   +1 more source

The Quinoline Photoremovable Group (PPG) Platform—A Medicinal Chemist's Approach for Photocage Development and Applications

Medicinal Research Reviews, EarlyView.
ABSTRACT Photoremovable protecting groups (PPGs) offer a straightforward solution for the temporary inactivation of biologically active substrates and their subsequent controlled release by light irradiation. Their relatively easy design and mode of application have made them useful tools for studying dynamic biological processes in vitro and in vivo ...
Bence Kontra, Zoltán Mucsi, Janez Ilaš, Petra Dunkel   +3 more
wiley   +1 more source

Influence of Selective Dopamine Agonist Ropinirole on Conditioned Place Preference and Somatic Signs of Morphine Withdrawal in Rats. [PDF]

Front Behav Neurosci, 2022
Shahzadi A, Shahzadi A, Yunusoglu O, Karabulut E, Sonmez H, Yazici Z.   +5 more
europepmc   +1 more source

Effects of intravenous injection of dopamine D2 receptor agonists on striatal neurons of rats.

, 1993
Hiroaki Matsubayashi, Taku Amano, Masashi Sasa   +2 more
openalex   +1 more source