Results 211 to 220 of about 554,589 (315)

The role of MAPK11/12/13/14 (p38 MAPK) protein in dopamine agonist-resistant prolactinomas. [PDF]

open access: yesBMC Endocr Disord, 2021
Wang S   +6 more
europepmc   +1 more source

Genetic and Pharmacological Inhibition of Metabotropic Glutamate Receptor Signalling Extends Lifespan in Drosophila

open access: yesAging Cell, EarlyView.
We show that genetic and pharmacological inhibition of the metabotropic glutamate receptor, DmGluRA extends Drosophila lifespan, improves stress tolerance and alters early‐life locomotion. Several markers indicative of reduced ribosomal biogenesis, a hallmark of longevity, were also detected in these flies.
Cui Guan   +4 more
wiley   +1 more source

Impulse control and correlation to dopamine agonist serum concentrations in people with Parkinson's disease. [PDF]

open access: yesJ Neurol
Staubo SC   +12 more
europepmc   +1 more source

Enhanced Microglial Engulfment of Dopaminergic Synapses Induces Parkinson's Disease‐Related Executive Dysfunction in an Acute LPC Infusion Targeting the mPFC

open access: yesAging Cell, EarlyView.
Parkinson's disease with executive dysfunction is a challenge. Our study reveals a novel pathway where abnormally elevated LPC induces miR‐2885/TDP‐43 signal activation in microglia, leading to dopaminergic terminal phagocytosis, and suggests that supplementing dopamine or inhibiting related microglial activation can mitigate the dysfunction, providing
Yehao Liu   +10 more
wiley   +1 more source

Sex-based disparities in dopamine agonist response in patients with restless legs syndrome. [PDF]

open access: yesJ Sleep Res
Mogavero MP   +9 more
europepmc   +1 more source

Blood phosphatidylethanol measurements indicate GLP‐1 receptor stimulation causes delayed decreases in alcohol consumption

open access: yesAlcohol, Clinical and Experimental Research, EarlyView.
Glucagon‐like peptide 1 receptor agonists (GLP‐1RAs) are effective for treating obesity (BMI ≥30) and are being investigated as a novel treatment for alcohol use disorder (AUD). This secondary analysis of a randomized clinical trial evaluated the effect of exenatide versus placebo on alcohol consumption using phosphatidylethanol (PEth) in 30 AUD ...
Mathias E. Jensen   +6 more
wiley   +1 more source

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