Results 231 to 240 of about 118,448 (336)

The Quinoline Photoremovable Group (PPG) Platform—A Medicinal Chemist's Approach for Photocage Development and Applications

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Photoremovable protecting groups (PPGs) offer a straightforward solution for the temporary inactivation of biologically active substrates and their subsequent controlled release by light irradiation. Their relatively easy design and mode of application have made them useful tools for studying dynamic biological processes in vitro and in vivo ...
Bence Kontra   +3 more
wiley   +1 more source

Distinct Residues in the Carboxyl Tail Mediate Agonist-induced Desensitization and Internalization of the Human Dopamine D1 Receptor [PDF]

open access: hybrid, 2002
Michael Lamey   +6 more
openalex   +1 more source

Molecular Tools to Study and Control Dopaminergic Neurotransmission With Light

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Dopaminergic neurotransmission is involved in several important brain functions, such as motor control, learning, reward‐motivated behavior, and emotions. Dysfunctions of dopaminergic system may lead to the development of various neurological and psychiatric disorders, like Parkinson's disease, schizophrenia, depression, and addictions ...
Galyna Maleeva   +5 more
wiley   +1 more source

Progress in Molecular Imprinting—From Inhibition of Enzymatic Activity to Regulation of Cellular Pathways

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Molecular imprinting is a very powerful tool in life science. The research areas benefiting from a wide range of capabilities of molecularly imprinted polymeric nanoparticles (nanoMIPs) include sample preparation, extraction, sensing/detection, diagnostics, and drug delivery.
Milada Vodova   +2 more
wiley   +1 more source

Role of astrocyte in neuroinflammation‐induced loss in neuroplasticity and subsequent onset of depression: A systematic review

open access: yesNeuroprotection, EarlyView.
Mechanistic crosstalk between microglia and astrocytes in major depressive disorder. Abstract Major depressive disorder (MDD) is a complex psychiatric condition increasingly linked to chronic neuroinflammation, particularly in the context of aging, stress, and systemic comorbidities.
Gaurav Singhal   +2 more
wiley   +1 more source

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