Results 241 to 250 of about 554,589 (315)

Dopamine Agonist Therapy in Advanced Parkinson’s Disease [PDF]

Journal of Movement Disorders, 2009
Heinz Reichmann
doaj   +1 more source

Effects of the dopamine D2 agonist, quinpirole, on time and number processing in rats [PDF]

, 2001
Angelo Santi, Romina Coppa, Lori E. Ross
openalex   +1 more source

Differential Effects of Direct and Indirect Dopamine Agonists on Prepulse Inhibition: A Study in D1 and D2 Receptor Knock-Out Mice [PDF]

, 2002
Rebecca J. Ralph-Williams, Virginia Lehmann-Masten, Veronica Otero-Corchón, Malcolm J. Low, Mark A. Geyer   +4 more
openalex   +1 more source

Differential G protein activation by the long and short isoforms of the dopamine D2 receptor

British Journal of Pharmacology, EarlyView.
Background and Purpose The dopamine D2 receptor is expressed as a short (D2S) and a long (D2L) isoform with 29 additional amino acids in the third intracellular loop. The D2S isoform shows higher presynaptic expression than the D2L isoform, and decreased D2S expression has recently been linked to an increased risk for schizophrenia.
David Reiner‐Link, Jakob Sture Madsen, David E. Gloriam, Hans Bräuner‐Osborne, Alexander S. Hauser   +4 more
wiley   +1 more source

Dopamine Agonist-Associated Hiccup in Parkinson's Disease: A Case Report. [PDF]

Noro Psikiyatr Ars, 2021
Emekli AS, Hanagasi HA.
europepmc   +1 more source

ERNEST COST action overview on the (patho)physiology of GPCRs and orphan GPCRs in the nervous system

British Journal of Pharmacology, EarlyView.
G protein‐coupled receptors (GPCRs) are a large family of cell surface receptors that play a critical role in nervous system function by transmitting signals between cells and their environment. They are involved in many, if not all, nervous system processes, and their dysfunction has been linked to various neurological disorders representing important
Necla Birgül Iyison, Clauda Abboud, Dayana Abboud, Abdulrasheed O. Abdulrahman, Ana‐Nicoleta Bondar, Julie Dam, Zafiroula Georgoussi, Jesús Giraldo, Anemari Horvat, Christos Karoussiotis, Alba Paz‐Castro, Miriam Scarpa, Hannes Schihada, Nicole Scholz, Bilge Güvenc Tuna, Nina Vardjan   +15 more
wiley   +1 more source

The Comparative Efficacy of Non-ergot Dopamine Agonist and Potential Risk Factors for Motor Complications and Side Effects From NEDA Use in Early Parkinson's Disease: Evidence From Clinical Trials. [PDF]

Front Aging Neurosci, 2022
Wu C, Guo H, Xu Y, Li L, Li X, Tang C, Chen D, Zhu M.   +7 more
europepmc   +1 more source

Distinct Residues in the Carboxyl Tail Mediate Agonist-induced Desensitization and Internalization of the Human Dopamine D1 Receptor [PDF]

, 2002
Michael Lamey, Miles D. Thompson, George Varghese, Hong Chi, Marek Sawzdargo, Susan R. George, Brian F. O’Dowd   +6 more
openalex   +1 more source

Relevance of G protein‐coupled receptor (GPCR) dynamics for receptor activation, signalling bias and allosteric modulation

British Journal of Pharmacology, EarlyView.
Abstract G protein‐coupled receptors (GPCRs) are one of the major drug targets. In recent years, computational drug design for GPCRs has mainly focused on static structures obtained through X‐ray crystallography, cryogenic electron microscopy (cryo‐EM) or in silico modelling as a starting point for virtual screening campaigns. However, GPCRs are highly
Marta Lopez‐Balastegui, Tomasz Maciej Stepniewski, Małgorzata M. Kogut‐Günthel, Antonella Di Pizio, Mette Marie Rosenkilde, Jiafei Mao, Jana Selent   +6 more
wiley   +1 more source