Results 271 to 280 of about 554,589 (315)

Adrogolide HCl (ABT‐431; DAS‐431), a Prodrug of the Dopamine D₁ Receptor Agonist, A‐86929: Preclinical Pharmacology and Clinical Data

, 2001
William J. Giardina, Michael Williams
openalex   +1 more source

Dopamine agonist treatment increases sensitivity to gamble outcomes in the hippocampus in de novo Parkinson's disease. [PDF]

Neuroimage Clin, 2020
van der Vegt JPM, Hulme OJ, Madsen KH, Buhmann C, Bloem BR, Münchau A, Helmich RC, Siebner HR.   +7 more
europepmc   +1 more source

Expanding the Phenotypic Spectrum of SPG7 Rare Damaging Variants: Insights From a Hungarian Cohort

Clinical Genetics, EarlyView.
Rare damaging SPG7 variants were detected in 58 patients with spastic paraplegia, ataxia, mitochondrial dysfunction, or motoneuron lesions. The cumulative prevalence of SPG7‐related conditions in Hungary was estimated. Phenotypic spectra and mitochondrial dysfunction were assessed in monoallelic and biallelic cases, contributing to the understanding of
Idris Janos Jimoh, Peter Balicza, Tamas Szlepak, Dora Csaban, Aniko Gal, Adrienn Geresi, Zoltan Grosz, Agnes Palasti, Judit Boczan, Peter Klivenyi, Maria Judit Molnar   +10 more
wiley   +1 more source

The Application of Polymeric Nanoparticles as Drug Delivery Carriers to Cells in Neurodegenerative Diseases

Cell Proliferation, EarlyView.
Polymeric nanoparticles represent promising drug (gene) delivery carriers to the brain due to their unique advantages to facilitate the penetration of blood–brain barrier and endocytosis of neuronal cells in neurodegenerative diseases. ABSTRACT In spite of great advances in modern medicine, there are a few effective strategies for the treatment of ...
Lian Jin, Libo Nie, Yan Deng, Ghulam Jilany Khana, Nongyue He   +4 more
wiley   +1 more source

Depression and Impulsivity Self-Assessment Tools to Identify Dopamine Agonist Side Effects in Patients With Pituitary Adenomas. [PDF]

Front Endocrinol (Lausanne), 2020
Hinojosa-Amaya JM, Johnson N, González-Torres C, Varlamov EV, Yedinak CG, McCartney S, Fleseriu M.   +6 more
europepmc   +1 more source

Human Midbrain Organoids Enriched With Dopaminergic Neurons for Long‐Term Functional Evaluation

Cell Proliferation, EarlyView.
We optimised a protocol that combines developmental patterning with mechanical cut to produce pint‐sized midbrain organoids, with diameters less than 300 μm, suitable for long‐term evaluation, along with a comprehensive functional assay system consisting of calcium transient assay, neurite extension assay, and multielectrode array assay. ABSTRACT Human
Xinyue Wang, Gaoying Sun, Mingming Tang, Da Li, Jianhuan Qi, Chuanyue Wang, Yukai Wang, Baoyang Hu   +7 more
wiley   +1 more source

Single dose of a dopamine agonist impairs reinforcement learning in humans: Behavioral evidence from a laboratory-based measure of reward responsiveness

Psychopharmacology, 2008
Citation Pizzagalli, Diego A, A. E. Evins, E. C. Schetter, M. Frank, Petra E. Pajtas, D. Santesso, Melissa, D. Pizzagalli, A. E. Evins, Melissa A. Culhane, Kyle Fullerton, Elena Ratner, Jeffrey Goetz, Birk   +14 more
semanticscholar   +1 more source

Effect of pergolide treatment on insulin dysregulation in horses and ponies with pituitary pars intermedia dysfunction

Equine Veterinary Journal, EarlyView.
Abstract Background Due to the high frequency of laminitis reported for both conditions, the relationship between pituitary pars intermedia dysfunction (PPID) and insulin dysregulation (ID), and the potential role of dopamine in modifying insulin secretion, requires further investigation.
Nicolas C. Galinelli, Nicholas J. Bamford, Madison L. Erdody, Skye A. Mackenzie, Tobias Warnken, Patricia A. Harris, Martin N. Sillence, Simon R. Bailey   +7 more
wiley   +1 more source