Results 21 to 30 of about 315,867 (288)

Infusion of D1 dopamine receptor agonist into medial frontal cortex disrupts neural correlates of interval timing

Frontiers in Behavioral Neuroscience, 2015
Medial frontal cortical (MFC) dopamine is essential for the organization of behavior in time. Our prior work indicates that blocking D1 dopamine receptors (D1DR) attenuates temporal processing and low-frequency oscillations by MFC neuronal networks ...
Krystal L Parker, Rafael N Ruggiero, Nandkumar S Narayanan   +2 more
doaj   +1 more source

A Role for Adenosine A1 Receptors in GABA and NMDA-Receptor Mediated Modulation of Dopamine Release: Studies Using Fast Cyclic Voltammetry

Sensors, 2008
In the striatum many neurotransmitters including GABA, glutamate, acetylcholine, dopamine, nitric oxide and adenosine interact to regulate synaptic transmission. Dopamine release in the striatum is regulated by a number of pre- and postsynaptic receptors
Carmel O’Neill, John J. O’Connor   +1 more
doaj   +1 more source

Clinical guidelines ‘Hyperprolactinemia’ (draft)

Ожирение и метаболизм, 2023
Hyperprolactinemia is a persistent excess of the blood serum prolactin. The syndrome contains various symptoms, the most characteristic is a violation of the reproductive system.
I. I. Dedov, G. A. Melnichenko, L. K. Dzeranova, E. N. Andreeva, E. N. Grineva, E. I. Marova, N. G. Mokrysheva, E. A. Pigarova, S. Y. Vorotnikova, N. S.  Fedorova, A. S. Shutova, E. G. Przhiyalkovskaya, I.  A.  Ilovaуskaya, T. I. Romantsova, S. A. Dogadin, L. A. Suplotova   +15 more
doaj   +1 more source

Aripiprazole-induced hyperprolactinemia in a young female with delusional disorder

Indian Journal of Psychological Medicine, 2016
Hyperprolactinemia is a common adverse effect of antipsychotic medication. Switching over to aripiprazole or adjunctive aripiprazole has been advocated for optimal management of antipsychotic-induced hyperprolactinemia.
Sam Padamadan Joseph
doaj   +1 more source

Enhancement in dopamine reduces generous behaviour in women.

PLoS ONE, 2019
Generosity is a human behavior common in social contexts. However, humans are not equally generous to everyone alike. Instead, generosity decreases as a function of social distance, an effect called social discounting.
Sergio Oroz Artigas, Lu Liu, Sabrina Strang, Caroline Burrasch, Astrid Hermsteiner, Thomas F Münte, Soyoung Q Park   +6 more
doaj   +1 more source

Mechanisms Underlying Dopaminergic Regulation of Nicotine-Induced Kinetic Tremor

Frontiers in Pharmacology, 2022
Nicotine induces kinetic tremor, which resembles pharmacological features of essential tremors, via activating the inferior olive (IO) neurons. Since nicotine is known to enhance dopamine release by stimulating α4β2 and/or α6 nACh receptors, we examined ...
Masaki Kato, Naofumi Kunisawa, Saki Shimizu, Higor A. Iha, Yukihiro Ohno   +4 more
doaj   +1 more source

In a Rush to Decide: Deep Brain Stimulation and Dopamine Agonist Therapy in Parkinson's Disease

Journal of Parkinson’s Disease, 2014
Background: It has been suggested that all patients with Parkinson's disease (PD) who undergo functional neurosurgery have difficulties in slowing down in high conflict tasks.
Atbin Djamshidian, Sean S. O'Sullivan, Alessandro Tomassini, Thomas Foltynie, Patricia Limousin, Iciar Aviles-Olmos, Thomas T. Warner, Andrew J. Lees, Bruno B. Averbeck   +8 more
doaj   +1 more source

Eckol as a Potential Therapeutic against Neurodegenerative Diseases Targeting Dopamine D₃/D₄ Receptors

Marine Drugs, 2019
The G protein-coupled receptor (GPCR) family of proteins comprises signaling proteins that mediate cellular responses to various hormones and neurotransmitters, and serves as a prime target for drug discovery.
Pradeep Paudel, Su Hui Seong, Sangwook Wu, Suhyun Park, Hyun Ah Jung, Jae Sue Choi   +5 more
doaj   +1 more source

A53T-alpha-synuclein overexpression impairs dopamine signaling and striatal synaptic plasticity in old mice [PDF]

, 2010
BACKGROUND: Parkinson's disease (PD), the second most frequent neurodegenerative disorder at old age, can be caused by elevated expression or the A53T missense mutation of the presynaptic protein alpha-synuclein (SNCA). PD is characterized pathologically
Liss Birgit, Paolo Calabresi, Auburger Georg, Silke Nuber, Javier Fernández-Ruiz, Lastres-Becker, Isabel, Double Kay L., Auburger, Georg, Lüddens Hartmut, Nuber Silke, Fernández-Ruiz, Javier, Fernández-Ruiz Javier, Gispert, Suzana, Schlaudraff Falk, Nuber, Silke, García-Arencibia Moisés, García-Arencibia, Moisés, Manfred Gerlach, Gerlach, Manfred, Double, Kay L., Kay L. Double, Alexander Kurz, Tantucci Michela, Bonin Michael, Bockhart, Vanessa, Gispert Suzana, Calabresi, Paolo, Lüddens, Hartmut, Moisés García-Arencibia, Tozzi Alessandro, Michael Bonin, Michela Tantucci, Schlaudraff, Falk, Hartmut Lüddens, Lastres-Becker Isabel, Isabel Lastres-Becker, Tantucci, Michela, Birgit Liss, Wüllner Ullrich, Ullrich Wüllner, Kurz Alexander, Vanessa Bockhart, Liss, Birgit, Falk Schlaudraff, Kurz, Alexander, Suzana Gispert, Bonin, Michael, Calabresi Paolo, Wüllner, Ullrich, Georg Auburger, Tozzi, Alessandro, Kay L Double, Alessandro Tozzi, Gerlach Manfred, Bockhart Vanessa   +54 more
core   +2 more sources

The Mechanism and Pathways of Dopamine and Dopamine Agonists in Prolactinomas [PDF]

Frontiers in Endocrinology, 2019
Dopamine agonists such as bromocriptine and cabergoline are the predominant treatment drugs for prolactinoma by inhibiting prolactin secretion and shrinking tumor size. However, the pathways of either dopamine or its agonists that lead to the death of cells are incompletely understood and some are even conflicting conclusions.
Xiaoshuang Liu, Chao Tang, Guodao Wen, Chunyu Zhong, Jin Yang, Junhao Zhu, Chiyuan Ma   +6 more
openaire   +3 more sources