Results 291 to 300 of about 554,589 (315)

Dopamine genetic risk scores and psychiatric symptoms: Interacting risk factors for impulse control behaviours in de novo Parkinson's disease

Journal of Neuropsychology, EarlyView.
Abstract Up to 45% of patients with Parkinson's disease (PD) experience impulse control disorders (ICDs), characterized by a loss of voluntary control over impulses, drives or temptations. This study aimed to investigate whether previously identified genetic and psychiatric risk factors interact towards the development of ICDs in PD.
Emma Whooley, Vincent Koppelmans, Hayley J. MacDonald, Alison Hall, Marit F. L. Ruitenberg   +4 more
wiley   +1 more source

Self‐care behaviours in patients with restless legs syndrome (RLS): development and psychometric testing of the RLS‐Self‐care Behaviour questionnaire

Journal of Sleep Research, EarlyView.
Summary Restless legs syndrome (RLS) is a highly prevalent condition that significantly disrupts sleep and causes reduced quality of life. While previous RLS research has mainly focused on the pharmacological treatment, this study presents the first instrument to measure self‐care, the RLS‐Self‐care Behaviour questionnaire (RLS‐ScBq).
Elzana Odzakovic, Christina Sandlund, Amanda Hellström, Martin Ulander, Kerstin Blom, Susanna Jernelöv, Viktor Kaldo, Maria Björk, Susanne Knutsson, Jonas Lind, Amir Pakpour, Anders Broström   +11 more
wiley   +1 more source

Autonomic Nervous System in Bone Remodeling: From Mechanisms to Novel Therapies in Orthopedic Diseases

Orthopaedic Surgery, EarlyView.
Due to the close connection between the autonomic nervous system and skeletal system, large amounts of evidence have shown that neuromodulation plays a crucial role in regulating bone metabolism. Clinically, neuromodulation has exhibited promising therapeutic effects in treating joint disorders by significantly reducing inflammation and clinical scores.
Ruihao Xia, Hongjun Peng, Xishan Zhu, Wangdui Suolang, Steve T. L. Pambayi, Xiao Yang, Yi Zeng, Bin Shen   +7 more
wiley   +1 more source

Phentolamine Infusion for the Treatment of Norepinephrine Extravasation in a Dog

Journal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Objective To describe a case of clinically significant norepinephrine extravasation in a dog with a successful outcome following the use of subcutaneous phentolamine infusion. Case Summary An 8‐year‐old male neutered Labrador Retriever experienced norepinephrine extravasation from a cephalic, peripheral intravenous catheter while under ...
Grace E. Flynn, Cody I. Riffe, Kathleen M. Aicher, Lance R. Wheeler   +3 more
wiley   +1 more source

Translating physiology of the arterial chemoreflex into novel therapeutic interventions targeting carotid bodies in cardiometabolic disorders

The Journal of Physiology, EarlyView.
Abstract figure legend The carotid body develops aberrant high activity in chronic heart failure, resistant hypertension, obstructive sleep apnoea (OSA) and diabetes. Hyperactivity of the carotid body leads to both high tonicity and increased sensitivity of the arterial chemoreflex with resultant sympathoexcitation.
Tymoteusz Żera, Bartłomiej Paleczny, Maciej Siński, Sílvia V. Conde, Krzysztof Narkiewicz, Piotr Ponikowski, Julian F.R. Paton, Piotr Niewiński   +7 more
wiley   +1 more source

Chemogenetic Control of Striatal Astrocytes Improves Parkinsonian Motor Deficits in Mice

Glia, Volume 73, Issue 6, Page 1188-1202, June 2025.
Main Points Dopamine depletion reduces locomotion‐induced calcium activity in dorsal striatal astrocytes. Chemogenetic activation facilitates astrocyte locomotion responses and improves motor behavior in dopamine lesioned animals. ABSTRACT Parkinson's disease (PD) is characterized by the degeneration of dopaminergic nigrostriatal inputs, which causes ...
Wesley R. Evans, Sindhuja S. Baskar, Angelica Vellore, Ana Raquel Castro E. Costa, Cynthia Jacob, Sanya Ravoori, Abimbola Arigbe, Rafiq Huda   +7 more
wiley   +1 more source

Medication equivalent dose program in R

Psychiatry and Clinical Neurosciences, EarlyView.
Shinsuke Koike, Yoji Hirano, Shinichiro Nakajima, Kentaro Morita   +3 more
wiley   +1 more source

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Impulse control disorder in patients with Parkinson's disease under dopamine agonist therapy: a multicentre study

Journal of Neurology Neurosurgery & Psychiatry, 2014
Background Impulse control disorders (ICDs) encompass a wide spectrum of abnormal behaviour frequently found in cases of Parkinson's disease (PD) treated with dopamine agonists (DAs).
P. Garcia-Ruiz, J. C. Martínez Castrillo, A. Alonso-Canovas, A. Herranz Bárcenas, L. Vela, P. Sánchez Alonso, M. Mata, Nuria Olmedilla Gonzalez, Ignacio Mahillo Fernández   +8 more
semanticscholar   +1 more source

Prolactinoma-associated headache and dopamine agonist treatment

Cephalalgia, 2014
Aim The aim of this article is to investigate the phenotype and etiology of prolactinoma-associated headache as well as present and discuss the plausible pain-relieving effect of dopamine agonist treatment. Methods In this case-based audit we included 11
M. Kallestrup, H. Kasch, Toke Østerby, E. Nielsen, T. Jensen, J. O. Jørgensen   +5 more
semanticscholar   +1 more source