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Switching and combining of dopamine agonists [PDF]
Dopamine agonists have been proved safe and effective as initial therapy in early stages of Parkinson's disease. Prospective long-term clinical trials demonstrated that initial symptomatic treatment with a dopamine agonist is associated with a significantly reduced risk for motor complications in comparison with levodopa therapy.
Theresa Glöckler+2 more
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Alopecia induced by dopamine agonists [PDF]
We report two women with PD who developed alopecia while being treated with the dopamine agonists pramipexole and ropinirole. The alopecia reversed partially after the drugs were discontinued. Both women were postmenopausal and had no history of hair loss or other dermatologic disorders.
Rowena E. Tabamo, Alessandro Di Rocco
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Dopamine and dopamine receptor agonists in cardiovascular therapy
Critical Care Medicine, 1990Dopamine (DA)--previously regarded simply as the precursor of norepinephrine--is now known to have its own unique effects on cardiovascular regulation which are mediated, in part, by activating specific DA receptors. DA has long been used in the treatment of shock and heart failure.
Michael B. Murphy, William J. Elliott
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Switching and combining dopamine agonists
Journal of Neural Transmission, 2003Switching from one dopamine agonist to another is common practice in the treatment of patients with Parkinson's disease. This paper describes some ideas on the most practical way to perform switching. In addition, it describes the possibilities of combining various dopamine agonists and discusses pros and cons for doing so.
B. Herting+3 more
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Ropinirole hydrochloride, a dopamine agonist
Acta Crystallographica Section C Crystal Structure Communications, 2006Ropinirole hydrochloride, or diethyl[2-(2-oxo-2,3-dihydro-1H-indol-4-yl)ethyl]ammonium chloride, C16H25N2O+.Cl-, belongs to a class of new non-ergoline dopamine agonists which bind specifically to D2-like receptors with a selectivity similar to that of dopamine (D3 > D2 > D4).
Krishnan Ravikumar+1 more
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Dopamine: Agonists and Neurodegenerative Disorders
Current Drug Targets, 2018Parkinson's disease (PD) is a neurodegenerative disease characterized by the loss of dopaminergic neurons within the substantia nigra pars compacta (SNpc). Despite many researches, there is still no cure for this disease. Levodopa is the first line treatment of PD, but the long term use of it leads to motor impairments and dyskinesias.
Yasir Hasan Siddique, Saba Khanam
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Dopamine agonists in Parkinson’s disease
Expert Review of Neurotherapeutics, 2008Dopamine agonists are established as effective drugs for the symptomatic treatment of Parkinson's disease (PD) throughout its course. As monotherapy, they produce effective control of motor symptoms and combine this with a low risk for motor complications.
Mitsutoshi Yamamoto+1 more
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Treatment of Acromegaly with Dopamine Agonists
Endocrinology and Metabolism Clinics of North America, 1992This article reviews the current understanding of how dopamine agonists stimulate growth hormone secretion in normal individuals, yet suppress growth hormone secretion in acromegaly patients. Although bromocriptine normalizes growth hormone or somatomedin C hypersecretion in a minority of patients, a significant number of subjects have a clinical ...
Craig A. Jaffe, Ariel L. Barkan
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Clinical Pharmacology of Dopamine Agonists
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2000With the availability of newer dopamine agonists selective for dopamine (D2) receptor subtypes, medical management of Parkinson's disease has progressed substantially. These agents can decrease the frequency of ergot‐related side effects and dyskinesias.
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Dopamine agonists and therapy compliance
Neurological Sciences, 2008Dopamine replacement therapy in Parkinson's disease improves motor symptoms, however some patients suffer from motor and behavioural disturbances attributable to taking doses of medication well beyond the dose required to treat their motor disabilities.
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