Further Characterization of Dopamine Release by Permeabilized PC 12 Cells [PDF]
Rat pheochromocytoma cells (PC 12) permeabilized with staphylococcal α-toxin release [3H]dopamine after addition of micromolar Ca2+. This does not require additional Mg2+-ATP (in contrast to bovine adrenal medullary chromaffin cells).
Ahnert-Hilger G. +18 more
core +1 more source
Tetraspanin (TSP-17) Protects Dopaminergic Neurons against 6-OHDA-Induced Neurodegeneration in C. elegans [PDF]
Parkinson's disease (PD), the second most prevalent neurodegenerative disease after Alzheimer's disease, is linked to the gradual loss of dopaminergic neurons in the substantia nigra.
A Garcia-Espana +75 more
core +9 more sources
Organic Cation Transporter 3 (OCT3) Is Localized to Intracellular and Surface Membranes in Select Glial and Neuronal Cells Within the Basolateral Amygdaloid Complex of Both Rats and Mice [PDF]
Organic cation transporter 3 (OCT3) is a high-capacity, low-affinity transporter that mediates corticosterone-sensitive uptake of monoamines including norepinephrine, epinephrine, dopamine, histamine and serotonin. OCT3 is expressed widely throughout the
Chan, June +3 more
core +2 more sources
Organic Cation Transporter 3: A Cellular Mechanism Underlying Rapid, Non-Genomic Glucocorticoid Regulation of Monoaminergic Neurotransmission, Physiology, and Behavior [PDF]
Corticosteroid hormones act at intracellular glucocorticoid receptors (GR) and mineralocorticoid receptors (MR) to alter gene expression, leading to diverse physiological and behavioral responses.
Gasser, Paul J., Lowry, Christopher A.
core +2 more sources
Filamin-A is required for the incorporation of tissue factor into cell-derived microvesicles [PDF]
We previously reported that the incorporation of tissue factor (TF) into cell-derived microvesicles (MVs) is regulated by the phosphorylation of the cytoplasmic domain of TF.
Collier, Mary E. W. +2 more
core +1 more source
GABA transporter function, oligomerization state, and anchoring: correlates with subcellularly resolved FRET [PDF]
The mouse γ-aminobutyric acid (GABA) transporter mGAT1 was expressed in neuroblastoma 2a cells. 19 mGAT1 designs incorporating fluorescent proteins were functionally characterized by [^3H]GABA uptake in assays that responded to several experimental ...
Abramoff +105 more
core +3 more sources
Defining the organizational structure of dopamine and muscarninic acetylcholine receptors [PDF]
No abstract ...
Alvarez-Curto, Elisa +4 more
core +1 more source
Superoxide Radical Dismutation as New Therapeutic Strategy in Parkinson’s Disease [PDF]
open4siAging is the biggest risk factor for developing many neurodegenerative disorders, including idiopathic Parkinson's disease (PD). PD is still an incurable disorder and the available medications are mainly directed to the treatment of symptoms in ...
core +1 more source
Inhibition of activity of GABA transporter GAT1 by δ-opioid receptor [PDF]
Analgesia is a well-documented effect of acupuncture. A critical role in pain sensation plays the nervous system, including the GABAergic system and opioid receptor (OR) activation.
Fucke, Thomas +7 more
core +2 more sources
Dopamine transporter (DAT) mutations are associated with neurological and psychiatric diseases, and DAT gene knockout in rats (DAT-KO) provides an opportunity to evaluate the DAT role in pathological conditions.
Anastasia N. Vaganova +3 more
doaj +1 more source

